Clinical implications for graft function of a new equation model for the ratio of living donor kidney volume to recipient body surface area

Chang Ki Lee, Young Eun Yoon, Kyung Hwa Choi, Seung Choul Yang, Joong Shik Lee, Dong Jin Joo, Kyu Ha Huh, Yu Seun Kim, Woong Kyu Han

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA). Materials and Methods: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors. Results: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m2, respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 mL/min at postoperative 12 months (p=0.005, p<0.001, and p=0.006). From the multiple linear regression equation and predicted probability from logistic regression, we could calculate the equation for the ratio of living donor kidney volume to recipient BSA on graft function. Conclusions: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.

Original languageEnglish
Pages (from-to)870-875
Number of pages6
JournalKorean Journal of Urology
Volume54
Issue number12
DOIs
Publication statusPublished - 2013 Dec 1

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Living Donors
Body Surface Area
Transplants
Kidney
Glomerular Filtration Rate
Tissue Donors
Kidney Transplantation
Diet Therapy
Linear Models
Logistic Models
Tomography
Demography
Physicians

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Lee, Chang Ki ; Yoon, Young Eun ; Choi, Kyung Hwa ; Yang, Seung Choul ; Lee, Joong Shik ; Joo, Dong Jin ; Huh, Kyu Ha ; Kim, Yu Seun ; Han, Woong Kyu. / Clinical implications for graft function of a new equation model for the ratio of living donor kidney volume to recipient body surface area. In: Korean Journal of Urology. 2013 ; Vol. 54, No. 12. pp. 870-875.
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abstract = "Purpose: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA). Materials and Methods: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors. Results: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m2, respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 mL/min at postoperative 12 months (p=0.005, p<0.001, and p=0.006). From the multiple linear regression equation and predicted probability from logistic regression, we could calculate the equation for the ratio of living donor kidney volume to recipient BSA on graft function. Conclusions: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.",
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Clinical implications for graft function of a new equation model for the ratio of living donor kidney volume to recipient body surface area. / Lee, Chang Ki; Yoon, Young Eun; Choi, Kyung Hwa; Yang, Seung Choul; Lee, Joong Shik; Joo, Dong Jin; Huh, Kyu Ha; Kim, Yu Seun; Han, Woong Kyu.

In: Korean Journal of Urology, Vol. 54, No. 12, 01.12.2013, p. 870-875.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinical implications for graft function of a new equation model for the ratio of living donor kidney volume to recipient body surface area

AU - Lee, Chang Ki

AU - Yoon, Young Eun

AU - Choi, Kyung Hwa

AU - Yang, Seung Choul

AU - Lee, Joong Shik

AU - Joo, Dong Jin

AU - Huh, Kyu Ha

AU - Kim, Yu Seun

AU - Han, Woong Kyu

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Purpose: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA). Materials and Methods: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors. Results: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m2, respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 mL/min at postoperative 12 months (p=0.005, p<0.001, and p=0.006). From the multiple linear regression equation and predicted probability from logistic regression, we could calculate the equation for the ratio of living donor kidney volume to recipient BSA on graft function. Conclusions: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.

AB - Purpose: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA). Materials and Methods: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors. Results: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m2, respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 mL/min at postoperative 12 months (p=0.005, p<0.001, and p=0.006). From the multiple linear regression equation and predicted probability from logistic regression, we could calculate the equation for the ratio of living donor kidney volume to recipient BSA on graft function. Conclusions: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.

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