Introduction: This study evaluated the clinical characteristics and survival rate after curative resection of young age pancreatic cancer patients using Korea Tumor Registry System Biliary Pancreas (KOTUS-BP) Database analysis. Methods: We compared demographics and clinical outcomes in patients under the age of 50 years (young age group) and those over the age of 65 years (standard group) between 1991 and 2017. We estimated the survival curve using the Kaplan–Meier method and the hazard ratio using the Cox proportional hazard model and 1:4 propensity matching analysis. Results: A total of 2470 patients were analyzed, including 2091 in the standard group and 379 in the young age group. Survival analysis showed a better overall survival in the recently enrolled patients (2011–2017) in both the young age and standard groups (p = 0.001 and p = 0.005, respectively). Between 2011 and 2017, recurrence-free survival was shorter in the young age group (p = 0.02), but the overall survival was not significantly different between the two groups (p = 0.94). Conclusions: Young-onset pancreatic cancer patients had more advanced stages at the time of diagnosis; however, the overall survival of both the young age and standard groups was similar due to adjuvant treatment after operation.
|Number of pages||9|
|Publication status||Published - 2023 Jan|
Bibliographical noteFunding Information:
In Seok Choi M.D. Ph. D, Konyang University Hospital, email@example.com. Sung-Sik Han, National Cancer Center, firstname.lastname@example.org, Keun Soo Ahn, Keimyung University Dongsan Hospital, email@example.com. Park Jae Woo, Daejeon St. Mary's Hospital, The Catholic University of Korea, firstname.lastname@example.org. Jae-Woon Choi, Chungbuk National University College of Medicine, email@example.com. Hyeon Kook Lee, Ewha Womans University, firstname.lastname@example.org. Jae Hoon Lee, University of Ulsan College of Medicine and Asan Medical Center email@example.com. Hyung Jun Kwon, Kyunpook National University Chilgolk Hospital, firstname.lastname@example.org. Kee Hwan Kim, Uijeongbu St. Mary's Hospital, The Catholic University of Korea email@example.com. Yang Seok Koh, Chonnam National University Medical School, firstname.lastname@example.org. Seong-Ryong Kim, Dongguk University Ilsan Hospital, email@example.com. Young-dong Yu, Korea University College of Medicine, firstname.lastname@example.org. Jae Do Yang, Jeonbuk National University Hospital, email@example.com. Seung Eun Lee, Chung-Ang University College of Medicine, firstname.lastname@example.org. Chang-Sup Lim, Seoul National University Boramae Medical Center email@example.com. Younghoon Roh, Dong-A University College of Medicine, firstname.lastname@example.org. Chi-Young Jeong, Gyeongsang national university, email@example.com.
© 2022 International Hepato-Pancreato-Biliary Association Inc.
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