Clinical outcome of pulmonary resections in patients with pulmonary metastasis of hepatocellular carcinoma

Kyung Kyu Kim, Ja Kyung Kim, doyoung kim, SangHoon Ahn, Chae Yoon Chon, Young Myoung Moon, Kyung Young Chung, KwangHyub Han

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Abstract

BACKGROUND/AIMS: Although the lung is the most common site of extrahepatic spread from hepatocellular carcinoma (HCC), the role of surgery for pulmonary metastasis remains unclear. The aim of this study was to evaluate the efficacy of pulmonary resection in patients with pulmonary metastasis from HCC. METHODS: Between July 2000 and July 2004, a total of 6 patients with pulmonary metastasis from HCC underwent curative pulmonary resections. The patients were divided into two groups (Surgery group and Non-surgery group) according to the primary treatment modality of HCC. Medical records, imaging studies, and pathologic reports of the surgical specimens were reviewed. RESULTS: Three patients in the surgery group underwent pulmonary resections for a solitary metastasis after hepatectomy for HCC, and they are all still alive. One of the 3 patients developed a tumor recurrence in the chest wall after pulmonary resection. The survival time after diagnosis of HCC were 79, 122, and 54 months, respectively. The survival time after pulmonary metastatectomy were 49, 39, and 20 months in the three patients. Another 3 patients in the non-surgery group, received a pulmonary metastatectomy; they had either a complete response HCC or partial radiologic response. These 3 patients developed recurrent disease in the liver. One of 3 patients died. The survival time after diagnosis of HCC were 153, 83, 12 months. The survival time after pulmonary metastatectomy were 51, 4, 2 months. CONCLUSIONS: The surgical resections of a solitary pulmonary metastasis from HCC in highly selected patients might be an effective treatment modalities for prolonged survival.

Original languageEnglish
Pages (from-to)350-358
Number of pages9
JournalThe Korean journal of hepatology
Volume11
Issue number4
Publication statusPublished - 2005 Jan 1

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Hepatocellular Carcinoma
Neoplasm Metastasis
Lung
Survival
Hepatectomy
Thoracic Wall
Diagnostic Imaging
Medical Records
Liver Diseases
Recurrence
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, Kyung Kyu ; Kim, Ja Kyung ; kim, doyoung ; Ahn, SangHoon ; Chon, Chae Yoon ; Moon, Young Myoung ; Chung, Kyung Young ; Han, KwangHyub. / Clinical outcome of pulmonary resections in patients with pulmonary metastasis of hepatocellular carcinoma. In: The Korean journal of hepatology. 2005 ; Vol. 11, No. 4. pp. 350-358.
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Clinical outcome of pulmonary resections in patients with pulmonary metastasis of hepatocellular carcinoma. / Kim, Kyung Kyu; Kim, Ja Kyung; kim, doyoung; Ahn, SangHoon; Chon, Chae Yoon; Moon, Young Myoung; Chung, Kyung Young; Han, KwangHyub.

In: The Korean journal of hepatology, Vol. 11, No. 4, 01.01.2005, p. 350-358.

Research output: Contribution to journalArticle

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AU - Kim, Ja Kyung

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AU - Moon, Young Myoung

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