Clinical practice guidelines for the management of atypical hemolytic uremic syndrome in Korea

Hae Il Cheong, Sang Kyung Jo, Sung Soo Yoon, Heeyeon Cho, Jin Seok Kim, Young Ok Kim, Ja Ryong Koo, Yong Park, Young Seo Park, Jae Il Shin, Kee Hwan Yoo, Doyeun Oh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a rare syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The major pathogenesis of aHUS involves dysregulation of the complement system. Eculizumab, which blocks complement C5 activation, has recently been proven as an effective agent. Delayed diagnosis and treatment of aHUS can cause death or end-stage renal disease. Therefore, a diagnosis that differentiates aHUS from other forms of thrombotic microangiopathy is very important for appropriate management. These guidelines aim to offer recommendations for the diagnosis and treatment of patients with aHUS in Korea. The guidelines have largely been adopted from the current guidelines due to the lack of evidence concerning the Korean population.

Original languageEnglish
Pages (from-to)1516-1528
Number of pages13
JournalJournal of Korean medical science
Volume31
Issue number10
DOIs
Publication statusPublished - 2016 Jan 1

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Practice Management
Korea
Practice Guidelines
Guidelines
Complement C5
Thrombotic Microangiopathies
Complement Activation
Delayed Diagnosis
Hemolytic Anemia
Acute Kidney Injury
Thrombocytopenia
Chronic Kidney Failure
Cause of Death
Atypical Hemolytic Uremic Syndrome
Therapeutics
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Cheong, Hae Il ; Jo, Sang Kyung ; Yoon, Sung Soo ; Cho, Heeyeon ; Kim, Jin Seok ; Kim, Young Ok ; Koo, Ja Ryong ; Park, Yong ; Park, Young Seo ; Shin, Jae Il ; Yoo, Kee Hwan ; Oh, Doyeun. / Clinical practice guidelines for the management of atypical hemolytic uremic syndrome in Korea. In: Journal of Korean medical science. 2016 ; Vol. 31, No. 10. pp. 1516-1528.
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Cheong, HI, Jo, SK, Yoon, SS, Cho, H, Kim, JS, Kim, YO, Koo, JR, Park, Y, Park, YS, Shin, JI, Yoo, KH & Oh, D 2016, 'Clinical practice guidelines for the management of atypical hemolytic uremic syndrome in Korea', Journal of Korean medical science, vol. 31, no. 10, pp. 1516-1528. https://doi.org/10.3346/jkms.2016.31.10.1516

Clinical practice guidelines for the management of atypical hemolytic uremic syndrome in Korea. / Cheong, Hae Il; Jo, Sang Kyung; Yoon, Sung Soo; Cho, Heeyeon; Kim, Jin Seok; Kim, Young Ok; Koo, Ja Ryong; Park, Yong; Park, Young Seo; Shin, Jae Il; Yoo, Kee Hwan; Oh, Doyeun.

In: Journal of Korean medical science, Vol. 31, No. 10, 01.01.2016, p. 1516-1528.

Research output: Contribution to journalArticle

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AU - Cheong, Hae Il

AU - Jo, Sang Kyung

AU - Yoon, Sung Soo

AU - Cho, Heeyeon

AU - Kim, Jin Seok

AU - Kim, Young Ok

AU - Koo, Ja Ryong

AU - Park, Yong

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AU - Shin, Jae Il

AU - Yoo, Kee Hwan

AU - Oh, Doyeun

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