Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: A nationwide multicenter prospective, endoscopy-based Study

Ki Nam Shim, Su Jin Hong, Jae Kyu Sung, Kyung Sik Park, Seong Eun Kim, Hyun Shin Park, Young Sun Kim, Seon Hee Lim, Chung Hyeon Kim, Min Jung Park, Jeong Yoon Yim, Kyung Ran Cho, Donghee Kim, Seun Ja Park, Sam Ryong Jee, Jin Il Kim, Joon Yong Park, Geun Am Song, Hwoon Yong Jung, Yong Chan LeeJae Gyu Kim, Jae J. Kim, Nayoung Kim, Soo Heon Park, Hyun Chae Jung, In Sik Chung

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Gastroesophageal reflux is a commonly encountered condition, but detailed data on reflux symptoms in Asian countries are lacking. Goals: To evaluate the prevalence and to document the clinical spectrum of endoscopic reflux esophagitis (RE). Study: A total 25,536 subjects underwent an upper gastrointestinal endoscopic examination as part of a health check, and completed a gastroesophageal reflux questionnaire. Endoscopic findings classified according to the Los Angeles (LA) classification and the data from gastroesophageal reflux questionnaire were analyzed. Results: On the basis of endoscopic findings, 2019 subjects (7.91%) were found to have RE: 5.87% in LA-A; 1.84% in LA-B; 0.18% in LA-C; and 0.02% in LA-D. Heartburn, acid regurgitation, chest pain, hoarseness, globus sensation, cough, and epigastric soreness were found to be associated with RE (P<0.05). Heartburn, acid regurgitation, and epigastric soreness were more frequent in LA-B than in LA-A (P<0.05). Epigastric soreness was most bothersome in LA-A and LA-B, and acid regurgitation was most bothersome in LA-C and LA-D (P<0.01). Heartburn, hoarseness, and globus sensation were more frequent in men with RE, and acid regurgitation was most common in women. Conclusions: The prevalence of RE was found to be 7.91% in Korea, and the profiles of reflux symptoms were found to depend on grade of RE and sex.

Original languageEnglish
Pages (from-to)632-638
Number of pages7
JournalJournal of Clinical Gastroenterology
Volume43
Issue number7
DOIs
Publication statusPublished - 2009 Aug

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Fingerprint Dive into the research topics of 'Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: A nationwide multicenter prospective, endoscopy-based Study'. Together they form a unique fingerprint.

  • Cite this

    Shim, K. N., Hong, S. J., Sung, J. K., Park, K. S., Kim, S. E., Park, H. S., Kim, Y. S., Lim, S. H., Kim, C. H., Park, M. J., Yim, J. Y., Cho, K. R., Kim, D., Park, S. J., Jee, S. R., Kim, J. I., Park, J. Y., Song, G. A., Jung, H. Y., ... Chung, I. S. (2009). Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: A nationwide multicenter prospective, endoscopy-based Study. Journal of Clinical Gastroenterology, 43(7), 632-638. https://doi.org/10.1097/MCG.0b013e3181855055