Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs

Soo Chan Kim, Kyu Joong Ahn, Seung Kyung Hann, Jin Wou Kim, Kyung Jeh Sung, Young Chul Kye, Nack In Kim, Kwang Hyun Cho, Kwang Joong Kim, Jail Il Youn

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: The abuse, misuse, and adverse effects to topical drugs have been widespread in Korea due to lack of awareness of seriousness of drug abuse and misuse, and improper designation of prescription and non-prescription drugs. Ohjective: This study was conducted to bring Korean people to an awareness of the abuse, misuse, and adverse effects of topical drugs, and to stress the importance of proper designation of non-prescription drugs. Methods: A multicenter, prospective, clinico-epidemiologic evaluation was made from patients with adverse effects to topical drugs who visited 31 dermatologic departments in university hospitals or private clinics nationwide from march, 2002 to December, 2002. Results: The diagnostic incidence of adverse effects from topical drugs are abuse and misuse (40%), dermatophytosis incognito (29%), bacterial infection (14%), contact dermatitis (9%), acne (2.5%), skin atrophy (1.4%), telangiectasia (1%). Erghty three percent of adverse effects are caused by topical corticosteroids, and betamethasone valerate, prednicarbate and triamcinolone acetonide are commonly used topical corticosteroids that induce adverse effects frequently. The most common way to obtain topical drugs is purchase directly from pharmacist without prescriptions. Conclusion: From this study, we confirmed that adverse effects to topical corticosteroids are very common even after the enforcement of designation of prescription drugs and non-prescription drugs. The proper designation of prescripton drugs should be reevaluated and based on the safety of patients to protect people from adverse effects of topical drugs.

Original languageEnglish
Pages (from-to)1129-1135
Number of pages7
JournalKorean Journal of Dermatology
Volume41
Issue number9
Publication statusPublished - 2003 Sep 1

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Epidemiologic Studies
Nonprescription Drugs
Pharmaceutical Preparations
Adrenal Cortex Hormones
Substance-Related Disorders
Prescriptions
Betamethasone Valerate
Drug Prescriptions
Triamcinolone Acetonide
Telangiectasis
Tinea
Prescription Drugs
Contact Dermatitis
Acne Vulgaris
Patient Safety
Korea
Pharmacists
Bacterial Infections
Atrophy
Skin

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Kim, S. C., Ahn, K. J., Hann, S. K., Kim, J. W., Sung, K. J., Kye, Y. C., ... Youn, J. I. (2003). Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs. Korean Journal of Dermatology, 41(9), 1129-1135.
Kim, Soo Chan ; Ahn, Kyu Joong ; Hann, Seung Kyung ; Kim, Jin Wou ; Sung, Kyung Jeh ; Kye, Young Chul ; Kim, Nack In ; Cho, Kwang Hyun ; Kim, Kwang Joong ; Youn, Jail Il. / Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs. In: Korean Journal of Dermatology. 2003 ; Vol. 41, No. 9. pp. 1129-1135.
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abstract = "Background: The abuse, misuse, and adverse effects to topical drugs have been widespread in Korea due to lack of awareness of seriousness of drug abuse and misuse, and improper designation of prescription and non-prescription drugs. Ohjective: This study was conducted to bring Korean people to an awareness of the abuse, misuse, and adverse effects of topical drugs, and to stress the importance of proper designation of non-prescription drugs. Methods: A multicenter, prospective, clinico-epidemiologic evaluation was made from patients with adverse effects to topical drugs who visited 31 dermatologic departments in university hospitals or private clinics nationwide from march, 2002 to December, 2002. Results: The diagnostic incidence of adverse effects from topical drugs are abuse and misuse (40{\%}), dermatophytosis incognito (29{\%}), bacterial infection (14{\%}), contact dermatitis (9{\%}), acne (2.5{\%}), skin atrophy (1.4{\%}), telangiectasia (1{\%}). Erghty three percent of adverse effects are caused by topical corticosteroids, and betamethasone valerate, prednicarbate and triamcinolone acetonide are commonly used topical corticosteroids that induce adverse effects frequently. The most common way to obtain topical drugs is purchase directly from pharmacist without prescriptions. Conclusion: From this study, we confirmed that adverse effects to topical corticosteroids are very common even after the enforcement of designation of prescription drugs and non-prescription drugs. The proper designation of prescripton drugs should be reevaluated and based on the safety of patients to protect people from adverse effects of topical drugs.",
author = "Kim, {Soo Chan} and Ahn, {Kyu Joong} and Hann, {Seung Kyung} and Kim, {Jin Wou} and Sung, {Kyung Jeh} and Kye, {Young Chul} and Kim, {Nack In} and Cho, {Kwang Hyun} and Kim, {Kwang Joong} and Youn, {Jail Il}",
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Kim, SC, Ahn, KJ, Hann, SK, Kim, JW, Sung, KJ, Kye, YC, Kim, NI, Cho, KH, Kim, KJ & Youn, JI 2003, 'Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs', Korean Journal of Dermatology, vol. 41, no. 9, pp. 1129-1135.

Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs. / Kim, Soo Chan; Ahn, Kyu Joong; Hann, Seung Kyung; Kim, Jin Wou; Sung, Kyung Jeh; Kye, Young Chul; Kim, Nack In; Cho, Kwang Hyun; Kim, Kwang Joong; Youn, Jail Il.

In: Korean Journal of Dermatology, Vol. 41, No. 9, 01.09.2003, p. 1129-1135.

Research output: Contribution to journalArticle

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T1 - Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs

AU - Kim, Soo Chan

AU - Ahn, Kyu Joong

AU - Hann, Seung Kyung

AU - Kim, Jin Wou

AU - Sung, Kyung Jeh

AU - Kye, Young Chul

AU - Kim, Nack In

AU - Cho, Kwang Hyun

AU - Kim, Kwang Joong

AU - Youn, Jail Il

PY - 2003/9/1

Y1 - 2003/9/1

N2 - Background: The abuse, misuse, and adverse effects to topical drugs have been widespread in Korea due to lack of awareness of seriousness of drug abuse and misuse, and improper designation of prescription and non-prescription drugs. Ohjective: This study was conducted to bring Korean people to an awareness of the abuse, misuse, and adverse effects of topical drugs, and to stress the importance of proper designation of non-prescription drugs. Methods: A multicenter, prospective, clinico-epidemiologic evaluation was made from patients with adverse effects to topical drugs who visited 31 dermatologic departments in university hospitals or private clinics nationwide from march, 2002 to December, 2002. Results: The diagnostic incidence of adverse effects from topical drugs are abuse and misuse (40%), dermatophytosis incognito (29%), bacterial infection (14%), contact dermatitis (9%), acne (2.5%), skin atrophy (1.4%), telangiectasia (1%). Erghty three percent of adverse effects are caused by topical corticosteroids, and betamethasone valerate, prednicarbate and triamcinolone acetonide are commonly used topical corticosteroids that induce adverse effects frequently. The most common way to obtain topical drugs is purchase directly from pharmacist without prescriptions. Conclusion: From this study, we confirmed that adverse effects to topical corticosteroids are very common even after the enforcement of designation of prescription drugs and non-prescription drugs. The proper designation of prescripton drugs should be reevaluated and based on the safety of patients to protect people from adverse effects of topical drugs.

AB - Background: The abuse, misuse, and adverse effects to topical drugs have been widespread in Korea due to lack of awareness of seriousness of drug abuse and misuse, and improper designation of prescription and non-prescription drugs. Ohjective: This study was conducted to bring Korean people to an awareness of the abuse, misuse, and adverse effects of topical drugs, and to stress the importance of proper designation of non-prescription drugs. Methods: A multicenter, prospective, clinico-epidemiologic evaluation was made from patients with adverse effects to topical drugs who visited 31 dermatologic departments in university hospitals or private clinics nationwide from march, 2002 to December, 2002. Results: The diagnostic incidence of adverse effects from topical drugs are abuse and misuse (40%), dermatophytosis incognito (29%), bacterial infection (14%), contact dermatitis (9%), acne (2.5%), skin atrophy (1.4%), telangiectasia (1%). Erghty three percent of adverse effects are caused by topical corticosteroids, and betamethasone valerate, prednicarbate and triamcinolone acetonide are commonly used topical corticosteroids that induce adverse effects frequently. The most common way to obtain topical drugs is purchase directly from pharmacist without prescriptions. Conclusion: From this study, we confirmed that adverse effects to topical corticosteroids are very common even after the enforcement of designation of prescription drugs and non-prescription drugs. The proper designation of prescripton drugs should be reevaluated and based on the safety of patients to protect people from adverse effects of topical drugs.

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