Clinicopathologic features of colorectal cancer combined with synchronous and metachronous gastric cancer

Hyun Jung Bok, Jin Ha Lee, Jae Kook Shin, Soung Min Jeon, Jae Jun Park, Chang Mo Moon, Sung Pil Hong, JaeHee Cheon, Tae Il Kim, Won Ho Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

BACKGROUND/AIMS: The purpose of this study was to investigate the clinicopathologic features of double primary cancers of the stomach and colorectum, compared to colorectal cancer alone.

METHODS: A retrospective analysis was made of 5,288 patients who underwent colorectal cancer surgery between January 2000 and December 2009 at Severance Hospital of Yonsei University. The clinicopathologic features were analyzed between 63 patients of double primary cancers and case-matched 126 patients of colorectal cancer alone. We classified double primary cancers into subgroups as premetachronous, synchronous and postmetachronous gastric cancer to identify differences between the three subgroups also.

RESULTS: Double primary cancers group showed 4.3 year-older age, lower BMI, and higher percentage of peritoneal metastasis, compared to colorectal cancer alone group. Overall and colorectal cancer specific survival did not have any significant difference between two groups. In histologic type of gastric cancer, a high percentage of undifferentiated adenocarcinoma (55.6%) and signet ring cell carcinoma (30.2%) were noted.

CONCLUSIONS: Double primary cancers of the stomach and colorectum had older-age onset, lower BMI and higher metastasis to peritoneum than colorectal cancer alone. Combined gastric cancer consisted of high percentage of undifferentiated and signet ring cell carcinomas.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume62
Issue number1
DOIs
Publication statusPublished - 2013 Jul 1

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Stomach Neoplasms
Colorectal Neoplasms
Signet Ring Cell Carcinoma
Neoplasm Metastasis
Neoplasms
Colorectal Surgery
Peritoneum
Age of Onset
Adenocarcinoma
Survival

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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Bok, Hyun Jung ; Lee, Jin Ha ; Shin, Jae Kook ; Jeon, Soung Min ; Park, Jae Jun ; Moon, Chang Mo ; Hong, Sung Pil ; Cheon, JaeHee ; Kim, Tae Il ; Kim, Won Ho. / Clinicopathologic features of colorectal cancer combined with synchronous and metachronous gastric cancer. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2013 ; Vol. 62, No. 1. pp. 27-32.
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Clinicopathologic features of colorectal cancer combined with synchronous and metachronous gastric cancer. / Bok, Hyun Jung; Lee, Jin Ha; Shin, Jae Kook; Jeon, Soung Min; Park, Jae Jun; Moon, Chang Mo; Hong, Sung Pil; Cheon, JaeHee; Kim, Tae Il; Kim, Won Ho.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 62, No. 1, 01.07.2013, p. 27-32.

Research output: Contribution to journalArticle

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T1 - Clinicopathologic features of colorectal cancer combined with synchronous and metachronous gastric cancer

AU - Bok, Hyun Jung

AU - Lee, Jin Ha

AU - Shin, Jae Kook

AU - Jeon, Soung Min

AU - Park, Jae Jun

AU - Moon, Chang Mo

AU - Hong, Sung Pil

AU - Cheon, JaeHee

AU - Kim, Tae Il

AU - Kim, Won Ho

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N2 - BACKGROUND/AIMS: The purpose of this study was to investigate the clinicopathologic features of double primary cancers of the stomach and colorectum, compared to colorectal cancer alone.METHODS: A retrospective analysis was made of 5,288 patients who underwent colorectal cancer surgery between January 2000 and December 2009 at Severance Hospital of Yonsei University. The clinicopathologic features were analyzed between 63 patients of double primary cancers and case-matched 126 patients of colorectal cancer alone. We classified double primary cancers into subgroups as premetachronous, synchronous and postmetachronous gastric cancer to identify differences between the three subgroups also.RESULTS: Double primary cancers group showed 4.3 year-older age, lower BMI, and higher percentage of peritoneal metastasis, compared to colorectal cancer alone group. Overall and colorectal cancer specific survival did not have any significant difference between two groups. In histologic type of gastric cancer, a high percentage of undifferentiated adenocarcinoma (55.6%) and signet ring cell carcinoma (30.2%) were noted.CONCLUSIONS: Double primary cancers of the stomach and colorectum had older-age onset, lower BMI and higher metastasis to peritoneum than colorectal cancer alone. Combined gastric cancer consisted of high percentage of undifferentiated and signet ring cell carcinomas.

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