Abstract
It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 152-159 |
| Number of pages | 8 |
| Journal | Yonsei Medical Journal |
| Volume | 43 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2002 Jan 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
}
Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -. / Chung, Kyung Young; Kim, SeHoon; Kwon, Il Hoon; Choi, Young Sik; Noh, Tae Woong; Kwon, Tae Jung; Shin, Dong Hwan.
In: Yonsei Medical Journal, Vol. 43, No. 2, 01.01.2002, p. 152-159.Research output: Contribution to journal › Article
TY - JOUR
T1 - Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -
AU - Chung, Kyung Young
AU - Kim, SeHoon
AU - Kwon, Il Hoon
AU - Choi, Young Sik
AU - Noh, Tae Woong
AU - Kwon, Tae Jung
AU - Shin, Dong Hwan
PY - 2002/1/1
Y1 - 2002/1/1
N2 - It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.
AB - It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.
UR - http://www.scopus.com/inward/record.url?scp=0036252210&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036252210&partnerID=8YFLogxK
U2 - 10.3349/ymj.2002.43.2.152
DO - 10.3349/ymj.2002.43.2.152
M3 - Article
C2 - 11971208
AN - SCOPUS:0036252210
VL - 43
SP - 152
EP - 159
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 2
ER -