Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -

Kyung Young Chung, SeHoon Kim, Il Hoon Kwon, Young Sik Choi, Tae Woong Noh, Tae Jung Kwon, Dong Hwan Shin

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.

Original languageEnglish
Pages (from-to)152-159
Number of pages8
JournalYonsei Medical Journal
Volume43
Issue number2
DOIs
Publication statusPublished - 2002 Jan 1

Fingerprint

Silicones
Pulmonary Embolism
Lung
Subcutaneous Injections
Embolism
Pneumonia
Injections
Adult Respiratory Distress Syndrome
Plastic Surgery
Korea
Respiratory Insufficiency
Lung Diseases
Blood Vessels
Autopsy
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Chung, Kyung Young ; Kim, SeHoon ; Kwon, Il Hoon ; Choi, Young Sik ; Noh, Tae Woong ; Kwon, Tae Jung ; Shin, Dong Hwan. / Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -. In: Yonsei Medical Journal. 2002 ; Vol. 43, No. 2. pp. 152-159.
@article{e77b1497567e4b07b54d3d0c4bb6c1eb,
title = "Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -",
abstract = "It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.",
author = "Chung, {Kyung Young} and SeHoon Kim and Kwon, {Il Hoon} and Choi, {Young Sik} and Noh, {Tae Woong} and Kwon, {Tae Jung} and Shin, {Dong Hwan}",
year = "2002",
month = "1",
day = "1",
doi = "10.3349/ymj.2002.43.2.152",
language = "English",
volume = "43",
pages = "152--159",
journal = "Yonsei Medical Journal",
issn = "0513-5796",
publisher = "Yonsei University College of Medicine",
number = "2",

}

Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -. / Chung, Kyung Young; Kim, SeHoon; Kwon, Il Hoon; Choi, Young Sik; Noh, Tae Woong; Kwon, Tae Jung; Shin, Dong Hwan.

In: Yonsei Medical Journal, Vol. 43, No. 2, 01.01.2002, p. 152-159.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung - A review of five cases -

AU - Chung, Kyung Young

AU - Kim, SeHoon

AU - Kwon, Il Hoon

AU - Choi, Young Sik

AU - Noh, Tae Woong

AU - Kwon, Tae Jung

AU - Shin, Dong Hwan

PY - 2002/1/1

Y1 - 2002/1/1

N2 - It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.

AB - It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the field of plastic surgery and, unfortunately, the illicit injection of silicone fluid by uncertified practitioners is not uncommon in Korea. We offer a critical pathologic review of 5 cases of pulmonary silicone embolism following illegal injection to the vaginal wall, four of which were fatal and came to legal autopsy. Our findings again confirm that subcutaneously injected silicone can gain access to the pulmonary vascular tree and cause pulmonary embolism. The histologic changes observed in the lung are variable and include four patterns i.e., the mere presence of silicone emboli, congestion and hemorrhage, acute pneumonitis, and diffuse alveolar damage despite the severe critical course in all cases. We were unable to find any histologic pattern that correlates well with the clinical course. Apart from producing emboli in the pulmonary vessels, subcutaneous injection of silicone can obviously cause serious pulmonary disease due to its ability to induce acute to induce acute pneumonitis and even possibly acute respiratory distress syndrome.

UR - http://www.scopus.com/inward/record.url?scp=0036252210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036252210&partnerID=8YFLogxK

U2 - 10.3349/ymj.2002.43.2.152

DO - 10.3349/ymj.2002.43.2.152

M3 - Article

VL - 43

SP - 152

EP - 159

JO - Yonsei Medical Journal

JF - Yonsei Medical Journal

SN - 0513-5796

IS - 2

ER -