Cognitive enhancing activity of Betula platyphylla sap in scopolamine induced amnesic mice

Seung Hyun Kim; Byung Ju Jeon; Dae Hyun Kim; Bo Ram Kim; Ki Yong Lee; Tae Bum Kim; Jung Hyun Park; Young Choong Kim; Sang Hyun Sung

Cognitive enhancing activity of Betula platyphylla sap in scopolamine induced amnesic mice

Seung Hyun Kim, Byung Ju Jeon, Dae Hyun Kim, Bo Ram Kim, Ki Yong Lee, Tae Bum Kim, Jung Hyun Park, Young Choong Kim, Sang Hyun Sung

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Cognitive enhancing activity of Betula platyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.

Original language	English
Pages (from-to)	50-53
Number of pages	4
Journal	Natural Product Sciences
Volume	16
Issue number	1
Publication status	Published - 2010 Mar

All Science Journal Classification (ASJC) codes

Drug Discovery
Organic Chemistry

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title = "Cognitive enhancing activity of Betula platyphylla sap in scopolamine induced amnesic mice",

abstract = "Cognitive enhancing activity of Betula platyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.",

author = "Kim, {Seung Hyun} and Jeon, {Byung Ju} and Kim, {Dae Hyun} and Kim, {Bo Ram} and Lee, {Ki Yong} and Kim, {Tae Bum} and Park, {Jung Hyun} and Kim, {Young Choong} and Sung, {Sang Hyun}",

year = "2010",

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language = "English",

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AU - Kim, Seung Hyun

AU - Jeon, Byung Ju

AU - Kim, Dae Hyun

AU - Kim, Bo Ram

AU - Lee, Ki Yong

AU - Kim, Tae Bum

AU - Park, Jung Hyun

AU - Kim, Young Choong

AU - Sung, Sang Hyun

PY - 2010/3

Y1 - 2010/3

N2 - Cognitive enhancing activity of Betula platyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.

AB - Cognitive enhancing activity of Betula platyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.

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