Cognitive enhancing activity of Betula platyphylla sap in scopolamine induced amnesic mice

Seung Hyun Kim, Byung Ju Jeon, Dae Hyun Kim, Bo Ram Kim, Ki Yong Lee, Tae Bum Kim, Jung Hyun Park, Young Choong Kim, Sang Hyun Sung

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Abstract

Cognitive enhancing activity of Betula platyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalNatural Product Sciences
Volume16
Issue number1
Publication statusPublished - 2010 Mar 1

All Science Journal Classification (ASJC) codes

  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Kim, S. H., Jeon, B. J., Kim, D. H., Kim, B. R., Lee, K. Y., Kim, T. B., Park, J. H., Kim, Y. C., & Sung, S. H. (2010). Cognitive enhancing activity of Betula platyphylla sap in scopolamine induced amnesic mice. Natural Product Sciences, 16(1), 50-53.