Colorectal flat neoplasia

Wo Ho Kim, Jung Hoon Suh, Tae Kim, Sung Kwan Shin, Yong Han Paik, Hae Won Chung, doyoung kim, Jae Hee Jeong, Jin Kyung Kang, Hoguen Kim, Namkyu Kim

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background and aims. An attempt has been made to evaluate the clinicopathological characteristics of flat colorectal neoplastic lesions, and analyse the factors associated with the malignancy. Patients and methods. A total of 115 flat neoplastic lesions, ≥5 mm in size, diagnosed in 87 patients by colonoscopy, were investigated. Results. The rectum was the most common location. Almost half (49.6%) of the flat neoplasms were small (5-10 mm), 27.8% were 11-20 mm and the remainder (22.6%) larger than 20 mm. The surface was smooth in 55.7%, granular in 20.0% and nodular in 24.3%. Histologically, the flat lesions were tubular, tubulovillous and villous adenomas in 69.6%, 20.9% and 5.2%, respectively. Five lesions (4.3%) were composed of carcinomas without adenoma. High-grade dysplasia, intramucosal carcinoma and invasive carcinoma were diagnosed in 9.6%, 7.8% and 6.1% of all flat neoplasms, respectively. Univariate analysis demonstrated that the location, size, surface pattern and histologic type of the flat lesions were factors associated with malignancy. However, in multivariate analysis, the size of the flat lesions was the only significant risk factor for malignant transformation. Conclusions. Flat neoplastic lesions of the colorectum have a relatively high rate of malignancy, and size is the most important factor associated with malignancy.

Original languageEnglish
Pages (from-to)165-171
Number of pages7
JournalDigestive and Liver Disease
Volume35
Issue number3
DOIs
Publication statusPublished - 2003 Mar 1

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Neoplasms
Carcinoma
Villous Adenoma
Colonoscopy
Rectum
Adenoma
Statistical Factor Analysis
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Kim, W. H., Suh, J. H., Kim, T., Shin, S. K., Paik, Y. H., Chung, H. W., ... Kim, N. (2003). Colorectal flat neoplasia. Digestive and Liver Disease, 35(3), 165-171. https://doi.org/10.1016/S1590-8658(03)00024-0
Kim, Wo Ho ; Suh, Jung Hoon ; Kim, Tae ; Shin, Sung Kwan ; Paik, Yong Han ; Chung, Hae Won ; kim, doyoung ; Jeong, Jae Hee ; Kang, Jin Kyung ; Kim, Hoguen ; Kim, Namkyu. / Colorectal flat neoplasia. In: Digestive and Liver Disease. 2003 ; Vol. 35, No. 3. pp. 165-171.
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abstract = "Background and aims. An attempt has been made to evaluate the clinicopathological characteristics of flat colorectal neoplastic lesions, and analyse the factors associated with the malignancy. Patients and methods. A total of 115 flat neoplastic lesions, ≥5 mm in size, diagnosed in 87 patients by colonoscopy, were investigated. Results. The rectum was the most common location. Almost half (49.6{\%}) of the flat neoplasms were small (5-10 mm), 27.8{\%} were 11-20 mm and the remainder (22.6{\%}) larger than 20 mm. The surface was smooth in 55.7{\%}, granular in 20.0{\%} and nodular in 24.3{\%}. Histologically, the flat lesions were tubular, tubulovillous and villous adenomas in 69.6{\%}, 20.9{\%} and 5.2{\%}, respectively. Five lesions (4.3{\%}) were composed of carcinomas without adenoma. High-grade dysplasia, intramucosal carcinoma and invasive carcinoma were diagnosed in 9.6{\%}, 7.8{\%} and 6.1{\%} of all flat neoplasms, respectively. Univariate analysis demonstrated that the location, size, surface pattern and histologic type of the flat lesions were factors associated with malignancy. However, in multivariate analysis, the size of the flat lesions was the only significant risk factor for malignant transformation. Conclusions. Flat neoplastic lesions of the colorectum have a relatively high rate of malignancy, and size is the most important factor associated with malignancy.",
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Kim, WH, Suh, JH, Kim, T, Shin, SK, Paik, YH, Chung, HW, kim, D, Jeong, JH, Kang, JK, Kim, H & Kim, N 2003, 'Colorectal flat neoplasia', Digestive and Liver Disease, vol. 35, no. 3, pp. 165-171. https://doi.org/10.1016/S1590-8658(03)00024-0

Colorectal flat neoplasia. / Kim, Wo Ho; Suh, Jung Hoon; Kim, Tae; Shin, Sung Kwan; Paik, Yong Han; Chung, Hae Won; kim, doyoung; Jeong, Jae Hee; Kang, Jin Kyung; Kim, Hoguen; Kim, Namkyu.

In: Digestive and Liver Disease, Vol. 35, No. 3, 01.03.2003, p. 165-171.

Research output: Contribution to journalArticle

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T1 - Colorectal flat neoplasia

AU - Kim, Wo Ho

AU - Suh, Jung Hoon

AU - Kim, Tae

AU - Shin, Sung Kwan

AU - Paik, Yong Han

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AU - kim, doyoung

AU - Jeong, Jae Hee

AU - Kang, Jin Kyung

AU - Kim, Hoguen

AU - Kim, Namkyu

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N2 - Background and aims. An attempt has been made to evaluate the clinicopathological characteristics of flat colorectal neoplastic lesions, and analyse the factors associated with the malignancy. Patients and methods. A total of 115 flat neoplastic lesions, ≥5 mm in size, diagnosed in 87 patients by colonoscopy, were investigated. Results. The rectum was the most common location. Almost half (49.6%) of the flat neoplasms were small (5-10 mm), 27.8% were 11-20 mm and the remainder (22.6%) larger than 20 mm. The surface was smooth in 55.7%, granular in 20.0% and nodular in 24.3%. Histologically, the flat lesions were tubular, tubulovillous and villous adenomas in 69.6%, 20.9% and 5.2%, respectively. Five lesions (4.3%) were composed of carcinomas without adenoma. High-grade dysplasia, intramucosal carcinoma and invasive carcinoma were diagnosed in 9.6%, 7.8% and 6.1% of all flat neoplasms, respectively. Univariate analysis demonstrated that the location, size, surface pattern and histologic type of the flat lesions were factors associated with malignancy. However, in multivariate analysis, the size of the flat lesions was the only significant risk factor for malignant transformation. Conclusions. Flat neoplastic lesions of the colorectum have a relatively high rate of malignancy, and size is the most important factor associated with malignancy.

AB - Background and aims. An attempt has been made to evaluate the clinicopathological characteristics of flat colorectal neoplastic lesions, and analyse the factors associated with the malignancy. Patients and methods. A total of 115 flat neoplastic lesions, ≥5 mm in size, diagnosed in 87 patients by colonoscopy, were investigated. Results. The rectum was the most common location. Almost half (49.6%) of the flat neoplasms were small (5-10 mm), 27.8% were 11-20 mm and the remainder (22.6%) larger than 20 mm. The surface was smooth in 55.7%, granular in 20.0% and nodular in 24.3%. Histologically, the flat lesions were tubular, tubulovillous and villous adenomas in 69.6%, 20.9% and 5.2%, respectively. Five lesions (4.3%) were composed of carcinomas without adenoma. High-grade dysplasia, intramucosal carcinoma and invasive carcinoma were diagnosed in 9.6%, 7.8% and 6.1% of all flat neoplasms, respectively. Univariate analysis demonstrated that the location, size, surface pattern and histologic type of the flat lesions were factors associated with malignancy. However, in multivariate analysis, the size of the flat lesions was the only significant risk factor for malignant transformation. Conclusions. Flat neoplastic lesions of the colorectum have a relatively high rate of malignancy, and size is the most important factor associated with malignancy.

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Kim WH, Suh JH, Kim T, Shin SK, Paik YH, Chung HW et al. Colorectal flat neoplasia. Digestive and Liver Disease. 2003 Mar 1;35(3):165-171. https://doi.org/10.1016/S1590-8658(03)00024-0