Combination self-assembly of β-sheet peptides and carbon nanotubes: Functionalizing carbon nanotubes with bioactive β-sheet block copolypeptides

Woo Jin Jeong, Yong Beom Lim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Understanding the self-assembly behavior of β-sheet peptides is important, not only in constructing bioactive peptide nanostructures, but also in inhibiting uncontrollable protein aggregation in protein-misfolding diseases. Here, the first systematic investigation of combination self-assembly between β-sheet block copolypeptides and CNTs is presented, demonstrating the presence of several different association modes during the combination self-assembly process. Bioactive β-sheet block copolypeptides can self-assemble by themselves, or can be used to functionalize CNT hybrids depending on the situation. This behavior may be important both for fabricating bioactive peptide/CNT hybrids and for controlling/inhibiting protein-misfolding diseases.

Original languageEnglish
Pages (from-to)49-54
Number of pages6
JournalMacromolecular Bioscience
Volume12
Issue number1
DOIs
Publication statusPublished - 2012 Jan 1

Fingerprint

Peptide Nanotubes
Carbon Nanotubes
Proteostasis Deficiencies
Self assembly
Peptides
Carbon nanotubes
Proteins
Nanostructures
Agglomeration

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

Cite this

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