Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients

Ju Jeong Jong, Sang Wook Kang, Ji Sup Yun, Yon Sung Tae, Chul Lee Seung, Sang Lee Yong, Kee Hyun Nam, Hang-Seok Chang, Youn Chung Woong, Soo Park Cheong

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Background: The aim of this study was to evaluate and compare the early surgical outcomes of endoscopic and conventional open thyroidectomies in patients with papillary thyroid microcarcinoma (PTMC). Methods: Between September 2005 and December 2007, 499 patients with PTMC were enrolled. 275 patients underwent gasless endoscopic thyroidectomy via the axillary route (endo group), and 224 patients underwent conventional open thyroidectomy (open group). We analyzed the patient's clinico-pathologic characteristics and surgical completeness between the two groups. Results: The endo group was younger than the open group.The open group underwentmore extensive surgery than the endo group.The operative timewas longer in the endogroup thanthe open group(138.5 ± 49.0 min vs. 105.5 ± 41.6 min; P < 0.0001), and a lessernumber of lymph nodeswere retrieved in the endo group compared to the open group (5.05 ± 2.94 vs. 5.96 ± 4.50, P = 0.007). We experienced complications in the endo group, such as transient hypocalcemia, transient RLN palsies, tracheal injuries, and esophageal injuries. There was no abnormal uptake on RAI scans in the two groups. From among patients who had undergone total thyroidectomy, all patients in the endo group had <1 ng/ml of serum Tg post-operatively; the seven patients in the open group had >1 ng/ml of serum Tg post-operatively. Tumor recurrence was detected in the open group only (n = 6). Also we checked the post-operative Tg in patients who had undergone lobectomy in the two groups, and found that there were no statistical differences in the two groups. Conclusions: According to our experience, gasless endoscopic thyroidectomy using a trans-axillary approach is a safe and feasible alternative to conventional open thyroidectomy in selected patients with PTMC.

Original languageEnglish
Pages (from-to)477-480
Number of pages4
JournalJournal of Surgical Oncology
Volume100
Issue number6
DOIs
Publication statusPublished - 2009 Nov 1

Fingerprint

Thyroidectomy
Papillary Thyroid Microcarcinoma
Recurrence
Serum
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Jong, Ju Jeong ; Kang, Sang Wook ; Yun, Ji Sup ; Tae, Yon Sung ; Seung, Chul Lee ; Yong, Sang Lee ; Nam, Kee Hyun ; Chang, Hang-Seok ; Woong, Youn Chung ; Cheong, Soo Park. / Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients. In: Journal of Surgical Oncology. 2009 ; Vol. 100, No. 6. pp. 477-480.
@article{98b6a03b4f354e679de01c58e9090bd6,
title = "Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients",
abstract = "Background: The aim of this study was to evaluate and compare the early surgical outcomes of endoscopic and conventional open thyroidectomies in patients with papillary thyroid microcarcinoma (PTMC). Methods: Between September 2005 and December 2007, 499 patients with PTMC were enrolled. 275 patients underwent gasless endoscopic thyroidectomy via the axillary route (endo group), and 224 patients underwent conventional open thyroidectomy (open group). We analyzed the patient's clinico-pathologic characteristics and surgical completeness between the two groups. Results: The endo group was younger than the open group.The open group underwentmore extensive surgery than the endo group.The operative timewas longer in the endogroup thanthe open group(138.5 ± 49.0 min vs. 105.5 ± 41.6 min; P < 0.0001), and a lessernumber of lymph nodeswere retrieved in the endo group compared to the open group (5.05 ± 2.94 vs. 5.96 ± 4.50, P = 0.007). We experienced complications in the endo group, such as transient hypocalcemia, transient RLN palsies, tracheal injuries, and esophageal injuries. There was no abnormal uptake on RAI scans in the two groups. From among patients who had undergone total thyroidectomy, all patients in the endo group had <1 ng/ml of serum Tg post-operatively; the seven patients in the open group had >1 ng/ml of serum Tg post-operatively. Tumor recurrence was detected in the open group only (n = 6). Also we checked the post-operative Tg in patients who had undergone lobectomy in the two groups, and found that there were no statistical differences in the two groups. Conclusions: According to our experience, gasless endoscopic thyroidectomy using a trans-axillary approach is a safe and feasible alternative to conventional open thyroidectomy in selected patients with PTMC.",
author = "Jong, {Ju Jeong} and Kang, {Sang Wook} and Yun, {Ji Sup} and Tae, {Yon Sung} and Seung, {Chul Lee} and Yong, {Sang Lee} and Nam, {Kee Hyun} and Hang-Seok Chang and Woong, {Youn Chung} and Cheong, {Soo Park}",
year = "2009",
month = "11",
day = "1",
doi = "10.1002/jso.21367",
language = "English",
volume = "100",
pages = "477--480",
journal = "Journal of Surgical Oncology",
issn = "0022-4790",
publisher = "Wiley-Liss Inc.",
number = "6",

}

Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients. / Jong, Ju Jeong; Kang, Sang Wook; Yun, Ji Sup; Tae, Yon Sung; Seung, Chul Lee; Yong, Sang Lee; Nam, Kee Hyun; Chang, Hang-Seok; Woong, Youn Chung; Cheong, Soo Park.

In: Journal of Surgical Oncology, Vol. 100, No. 6, 01.11.2009, p. 477-480.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparative study of endoscopic thyroidectomy versus conventional open thyroidectomy in papillary thyroid microcarcinoma (PTMC) patients

AU - Jong, Ju Jeong

AU - Kang, Sang Wook

AU - Yun, Ji Sup

AU - Tae, Yon Sung

AU - Seung, Chul Lee

AU - Yong, Sang Lee

AU - Nam, Kee Hyun

AU - Chang, Hang-Seok

AU - Woong, Youn Chung

AU - Cheong, Soo Park

PY - 2009/11/1

Y1 - 2009/11/1

N2 - Background: The aim of this study was to evaluate and compare the early surgical outcomes of endoscopic and conventional open thyroidectomies in patients with papillary thyroid microcarcinoma (PTMC). Methods: Between September 2005 and December 2007, 499 patients with PTMC were enrolled. 275 patients underwent gasless endoscopic thyroidectomy via the axillary route (endo group), and 224 patients underwent conventional open thyroidectomy (open group). We analyzed the patient's clinico-pathologic characteristics and surgical completeness between the two groups. Results: The endo group was younger than the open group.The open group underwentmore extensive surgery than the endo group.The operative timewas longer in the endogroup thanthe open group(138.5 ± 49.0 min vs. 105.5 ± 41.6 min; P < 0.0001), and a lessernumber of lymph nodeswere retrieved in the endo group compared to the open group (5.05 ± 2.94 vs. 5.96 ± 4.50, P = 0.007). We experienced complications in the endo group, such as transient hypocalcemia, transient RLN palsies, tracheal injuries, and esophageal injuries. There was no abnormal uptake on RAI scans in the two groups. From among patients who had undergone total thyroidectomy, all patients in the endo group had <1 ng/ml of serum Tg post-operatively; the seven patients in the open group had >1 ng/ml of serum Tg post-operatively. Tumor recurrence was detected in the open group only (n = 6). Also we checked the post-operative Tg in patients who had undergone lobectomy in the two groups, and found that there were no statistical differences in the two groups. Conclusions: According to our experience, gasless endoscopic thyroidectomy using a trans-axillary approach is a safe and feasible alternative to conventional open thyroidectomy in selected patients with PTMC.

AB - Background: The aim of this study was to evaluate and compare the early surgical outcomes of endoscopic and conventional open thyroidectomies in patients with papillary thyroid microcarcinoma (PTMC). Methods: Between September 2005 and December 2007, 499 patients with PTMC were enrolled. 275 patients underwent gasless endoscopic thyroidectomy via the axillary route (endo group), and 224 patients underwent conventional open thyroidectomy (open group). We analyzed the patient's clinico-pathologic characteristics and surgical completeness between the two groups. Results: The endo group was younger than the open group.The open group underwentmore extensive surgery than the endo group.The operative timewas longer in the endogroup thanthe open group(138.5 ± 49.0 min vs. 105.5 ± 41.6 min; P < 0.0001), and a lessernumber of lymph nodeswere retrieved in the endo group compared to the open group (5.05 ± 2.94 vs. 5.96 ± 4.50, P = 0.007). We experienced complications in the endo group, such as transient hypocalcemia, transient RLN palsies, tracheal injuries, and esophageal injuries. There was no abnormal uptake on RAI scans in the two groups. From among patients who had undergone total thyroidectomy, all patients in the endo group had <1 ng/ml of serum Tg post-operatively; the seven patients in the open group had >1 ng/ml of serum Tg post-operatively. Tumor recurrence was detected in the open group only (n = 6). Also we checked the post-operative Tg in patients who had undergone lobectomy in the two groups, and found that there were no statistical differences in the two groups. Conclusions: According to our experience, gasless endoscopic thyroidectomy using a trans-axillary approach is a safe and feasible alternative to conventional open thyroidectomy in selected patients with PTMC.

UR - http://www.scopus.com/inward/record.url?scp=70350335378&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350335378&partnerID=8YFLogxK

U2 - 10.1002/jso.21367

DO - 10.1002/jso.21367

M3 - Article

VL - 100

SP - 477

EP - 480

JO - Journal of Surgical Oncology

JF - Journal of Surgical Oncology

SN - 0022-4790

IS - 6

ER -