Comparison between Ultrasonography and Galactography in Detecting Lesions in Patients with Pathologic Nipple Discharge

Hyun Kyung Jung, Young Mi Park, Hye Jin Baek, Hye Jung Choo, Eunkyung Kim, Dong Wook Kim, Sun Joo Lee, Jin Hwa Lee

Research output: Contribution to journalArticle

Abstract

Purpose This study aimed to compare the diagnostic performance of breast ultrasonography (US) with that of galactography in the detection of lesions in patients with pathologic nipple discharge. Methods We included 46 cases from 39 patients (all women; mean age, 44.0 years; range, 22-68 years) who had pathologic nipple discharge and underwent US and galactography between March 2004 and December 2012. Two radiologists retrospectively reviewed and compared the detectability of lesions on US and galactography images. A receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of US and galactography, and the area under the curve was compared between the 2 imaging modalities. Results A total of 35 cases were pathologically diagnosed. Out of 11 cases that completed a follow-up, none developed malignancies during the follow-up period (mean: 63.5 months; range: 34.8-125.7 months). The sensitivity, specificity, and positive and negative predictive values of US with respect to detectability of lesions were 75%, 42.9%, 11.1%, and 94.7%, respectively, and those of galactography were 100%, 38.1%, 13.3%, and 100%, respectively. Conclusions Galactography is more sensitive than US in the detection of lesions in patients with pathologic nipple discharge.

Original languageEnglish
Pages (from-to)93-98
Number of pages6
JournalUltrasound Quarterly
Volume35
Issue number1
DOIs
Publication statusPublished - 2019 Mar 1

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Ultrasonography
Mammary Ultrasonography
ROC Curve
Area Under Curve
Nipple Discharge
Sensitivity and Specificity
Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Jung, Hyun Kyung ; Park, Young Mi ; Baek, Hye Jin ; Choo, Hye Jung ; Kim, Eunkyung ; Kim, Dong Wook ; Lee, Sun Joo ; Lee, Jin Hwa. / Comparison between Ultrasonography and Galactography in Detecting Lesions in Patients with Pathologic Nipple Discharge. In: Ultrasound Quarterly. 2019 ; Vol. 35, No. 1. pp. 93-98.
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abstract = "Purpose This study aimed to compare the diagnostic performance of breast ultrasonography (US) with that of galactography in the detection of lesions in patients with pathologic nipple discharge. Methods We included 46 cases from 39 patients (all women; mean age, 44.0 years; range, 22-68 years) who had pathologic nipple discharge and underwent US and galactography between March 2004 and December 2012. Two radiologists retrospectively reviewed and compared the detectability of lesions on US and galactography images. A receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of US and galactography, and the area under the curve was compared between the 2 imaging modalities. Results A total of 35 cases were pathologically diagnosed. Out of 11 cases that completed a follow-up, none developed malignancies during the follow-up period (mean: 63.5 months; range: 34.8-125.7 months). The sensitivity, specificity, and positive and negative predictive values of US with respect to detectability of lesions were 75{\%}, 42.9{\%}, 11.1{\%}, and 94.7{\%}, respectively, and those of galactography were 100{\%}, 38.1{\%}, 13.3{\%}, and 100{\%}, respectively. Conclusions Galactography is more sensitive than US in the detection of lesions in patients with pathologic nipple discharge.",
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Comparison between Ultrasonography and Galactography in Detecting Lesions in Patients with Pathologic Nipple Discharge. / Jung, Hyun Kyung; Park, Young Mi; Baek, Hye Jin; Choo, Hye Jung; Kim, Eunkyung; Kim, Dong Wook; Lee, Sun Joo; Lee, Jin Hwa.

In: Ultrasound Quarterly, Vol. 35, No. 1, 01.03.2019, p. 93-98.

Research output: Contribution to journalArticle

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N2 - Purpose This study aimed to compare the diagnostic performance of breast ultrasonography (US) with that of galactography in the detection of lesions in patients with pathologic nipple discharge. Methods We included 46 cases from 39 patients (all women; mean age, 44.0 years; range, 22-68 years) who had pathologic nipple discharge and underwent US and galactography between March 2004 and December 2012. Two radiologists retrospectively reviewed and compared the detectability of lesions on US and galactography images. A receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of US and galactography, and the area under the curve was compared between the 2 imaging modalities. Results A total of 35 cases were pathologically diagnosed. Out of 11 cases that completed a follow-up, none developed malignancies during the follow-up period (mean: 63.5 months; range: 34.8-125.7 months). The sensitivity, specificity, and positive and negative predictive values of US with respect to detectability of lesions were 75%, 42.9%, 11.1%, and 94.7%, respectively, and those of galactography were 100%, 38.1%, 13.3%, and 100%, respectively. Conclusions Galactography is more sensitive than US in the detection of lesions in patients with pathologic nipple discharge.

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