Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases

Korea Acute Myocardial Infarction Registry Investigators

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: The clinical significance of complete revascularization for ST segment elevation myocardial infarction (STEMI) patients during admission is still debatable. Methods: A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention (PPCI) were analyzed. We used propensity score matching (PSM) to control differences of baseline characteristics between culprit only intervention (CP) and multivessel percutaneous coronary interventions (MP), and between double vessel disease (DVD) and triple vessel disease (TVD). The major adverse cardiac event (MACE) was analyzed for one year after discharge. Results: TVD patients showed higher incidence of MACE (14.2% vs. 8.6%, P = 0.01), any cause of revascularization (10.6% vs. 5.9%, P = 0.01), and repeated PCI (9.5% vs. 5.7%, P = 0.02), as compared to DVD patients during one year after discharge. MP reduced MACE effectively (7.3% vs. 13.8%, P = 0.03), as compared to CP for one year, but all cause of death (1.6% vs. 3.2%, P = 0.38), MI (0.4% vs. 0.8%, P = 1.00), and any cause of revascularization (5.3% vs. 9.7%, P = 0.09) were comparable in the two treatment groups. Conclusions: STEMI patients with TVD showed higher rate of MACE, as compared to DVD. MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.

Original languageEnglish
Pages (from-to)208-217
Number of pages10
JournalJournal of Geriatric Cardiology
Volume12
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Percutaneous Coronary Intervention
Coronary Disease
Myocardial Infarction
Cardiogenic Shock
Propensity Score
Patient Admission
ST Elevation Myocardial Infarction
Registries
Cause of Death
Databases
Incidence
Therapeutics

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology
  • Cardiology and Cardiovascular Medicine

Cite this

@article{a1fb4a9efaf54e0db0fa555b38e6555e,
title = "Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases",
abstract = "Background: The clinical significance of complete revascularization for ST segment elevation myocardial infarction (STEMI) patients during admission is still debatable. Methods: A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention (PPCI) were analyzed. We used propensity score matching (PSM) to control differences of baseline characteristics between culprit only intervention (CP) and multivessel percutaneous coronary interventions (MP), and between double vessel disease (DVD) and triple vessel disease (TVD). The major adverse cardiac event (MACE) was analyzed for one year after discharge. Results: TVD patients showed higher incidence of MACE (14.2{\%} vs. 8.6{\%}, P = 0.01), any cause of revascularization (10.6{\%} vs. 5.9{\%}, P = 0.01), and repeated PCI (9.5{\%} vs. 5.7{\%}, P = 0.02), as compared to DVD patients during one year after discharge. MP reduced MACE effectively (7.3{\%} vs. 13.8{\%}, P = 0.03), as compared to CP for one year, but all cause of death (1.6{\%} vs. 3.2{\%}, P = 0.38), MI (0.4{\%} vs. 0.8{\%}, P = 1.00), and any cause of revascularization (5.3{\%} vs. 9.7{\%}, P = 0.09) were comparable in the two treatment groups. Conclusions: STEMI patients with TVD showed higher rate of MACE, as compared to DVD. MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.",
author = "{Korea Acute Myocardial Infarction Registry Investigators} and Ryu, {Kwang Sun} and Park, {Hyun Woo} and Park, {Soo Ho} and Shon, {Ho Sun} and Ryu, {Keun Ho} and Lee, {Dong Gyu} and Bashir, {Mohamed E.A.} and Lee, {Ju Hee} and Kim, {Sang Min} and Lee, {Sang Yeub} and Bae, {Jang Whan} and Hwang, {Kyung Kuk} and Kim, {Dong Woon} and Cho, {Myeong Chan} and Ahn, {Young Keun} and Jeong, {Myung Ho} and Kim, {Chong Jin} and Park, {Jong Seon} and Kim, {Young Jo} and Jang, {Yang Soo} and Kim, {Hyo Soo} and Seung, {Ki Bae}",
year = "2015",
month = "1",
day = "1",
doi = "10.11909/j.issn.1671-5411.2015.03.014",
language = "English",
volume = "12",
pages = "208--217",
journal = "Journal of Geriatric Cardiology",
issn = "1671-5411",
publisher = "Institute of Geriatric Cardiology",
number = "3",

}

Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases. / Korea Acute Myocardial Infarction Registry Investigators.

In: Journal of Geriatric Cardiology, Vol. 12, No. 3, 01.01.2015, p. 208-217.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases

AU - Korea Acute Myocardial Infarction Registry Investigators

AU - Ryu, Kwang Sun

AU - Park, Hyun Woo

AU - Park, Soo Ho

AU - Shon, Ho Sun

AU - Ryu, Keun Ho

AU - Lee, Dong Gyu

AU - Bashir, Mohamed E.A.

AU - Lee, Ju Hee

AU - Kim, Sang Min

AU - Lee, Sang Yeub

AU - Bae, Jang Whan

AU - Hwang, Kyung Kuk

AU - Kim, Dong Woon

AU - Cho, Myeong Chan

AU - Ahn, Young Keun

AU - Jeong, Myung Ho

AU - Kim, Chong Jin

AU - Park, Jong Seon

AU - Kim, Young Jo

AU - Jang, Yang Soo

AU - Kim, Hyo Soo

AU - Seung, Ki Bae

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Background: The clinical significance of complete revascularization for ST segment elevation myocardial infarction (STEMI) patients during admission is still debatable. Methods: A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention (PPCI) were analyzed. We used propensity score matching (PSM) to control differences of baseline characteristics between culprit only intervention (CP) and multivessel percutaneous coronary interventions (MP), and between double vessel disease (DVD) and triple vessel disease (TVD). The major adverse cardiac event (MACE) was analyzed for one year after discharge. Results: TVD patients showed higher incidence of MACE (14.2% vs. 8.6%, P = 0.01), any cause of revascularization (10.6% vs. 5.9%, P = 0.01), and repeated PCI (9.5% vs. 5.7%, P = 0.02), as compared to DVD patients during one year after discharge. MP reduced MACE effectively (7.3% vs. 13.8%, P = 0.03), as compared to CP for one year, but all cause of death (1.6% vs. 3.2%, P = 0.38), MI (0.4% vs. 0.8%, P = 1.00), and any cause of revascularization (5.3% vs. 9.7%, P = 0.09) were comparable in the two treatment groups. Conclusions: STEMI patients with TVD showed higher rate of MACE, as compared to DVD. MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.

AB - Background: The clinical significance of complete revascularization for ST segment elevation myocardial infarction (STEMI) patients during admission is still debatable. Methods: A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention (PPCI) were analyzed. We used propensity score matching (PSM) to control differences of baseline characteristics between culprit only intervention (CP) and multivessel percutaneous coronary interventions (MP), and between double vessel disease (DVD) and triple vessel disease (TVD). The major adverse cardiac event (MACE) was analyzed for one year after discharge. Results: TVD patients showed higher incidence of MACE (14.2% vs. 8.6%, P = 0.01), any cause of revascularization (10.6% vs. 5.9%, P = 0.01), and repeated PCI (9.5% vs. 5.7%, P = 0.02), as compared to DVD patients during one year after discharge. MP reduced MACE effectively (7.3% vs. 13.8%, P = 0.03), as compared to CP for one year, but all cause of death (1.6% vs. 3.2%, P = 0.38), MI (0.4% vs. 0.8%, P = 1.00), and any cause of revascularization (5.3% vs. 9.7%, P = 0.09) were comparable in the two treatment groups. Conclusions: STEMI patients with TVD showed higher rate of MACE, as compared to DVD. MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.

UR - http://www.scopus.com/inward/record.url?scp=84929920673&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929920673&partnerID=8YFLogxK

U2 - 10.11909/j.issn.1671-5411.2015.03.014

DO - 10.11909/j.issn.1671-5411.2015.03.014

M3 - Article

AN - SCOPUS:84929920673

VL - 12

SP - 208

EP - 217

JO - Journal of Geriatric Cardiology

JF - Journal of Geriatric Cardiology

SN - 1671-5411

IS - 3

ER -