Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina

Jang Hee Ye, Kyunghwan Kim, Yong Sook Goo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

Retinal prosthesis is regarded as a promising method for restoring vision for the blind with retinal diseases such as retinitis pigmentosa (RP) and age related macular degeneration (ARMD). Among the several prerequisites for retinal prosthesis to succeed, one of the most important factors is the optimization of electrical stimulation applied through the prosthesis. From the previous study, we showed that the electrical characteristics of diseased retina are different from those of normal retina. For the next step, we compared electrically evoked response properties of retinal ganglion cells and established the thresholds for charge density in normal and rd1 mouse using multi-electrode array (MEA). The threshold for charge density was higher in rd1 mouse. The mean values were 254.78 μC/cm2 and 424.62 μC/cm2 in normal and rd1 mouse, respectively.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages2465-2468
Number of pages4
Publication statusPublished - 2008 Dec 1
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 2008 Aug 202008 Aug 25

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period08/8/2008/8/25

Fingerprint

Visual Prosthesis
Ganglia
Retina
Charge density
Retinal Diseases
Retinitis Pigmentosa
Retinal Ganglion Cells
Macular Degeneration
Electric Stimulation
Prostheses and Implants
Electrodes

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Ye, J. H., Kim, K., & Goo, Y. S. (2008). Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 2465-2468). [4649699]
Ye, Jang Hee ; Kim, Kyunghwan ; Goo, Yong Sook. / Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. pp. 2465-2468
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Ye, JH, Kim, K & Goo, YS 2008, Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08., 4649699, pp. 2465-2468, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 08/8/20.

Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina. / Ye, Jang Hee; Kim, Kyunghwan; Goo, Yong Sook.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 2465-2468 4649699.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Ye JH, Kim K, Goo YS. Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 2465-2468. 4649699