Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones

Jin Seok Park, Seok Jeong, DongKi Lee, Sung Ill Jang, Tae Hoon Lee, Sang Heum Park, Jae Chul Hwang, Jin Hong Kim, Byoung Moo Yoo, Shin Goo Park, Don Haeng Lee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of large common bile duct (CBD) stones. However, it remains unclear how the outcomes of EPLBD alone compare with those of EPLBD with EST. In this study, we assessed the safety and therapeutic outcomes of EPLBD with vs. without EST for the removal of large bile duct stones. Methods This prospective, multicenter study was conducted on 200 patients with bile duct stones of ≥10mm in diameter. Patients were randomly assigned to an EPLBD alone group (n=100) or an EPLBD with EST group (n=100). These two groups were compared with respect to overall procedure-related adverse events, overall stone removal success rate, number of endoscopic sessions required for complete stone removal, need for mechanical lithotripsy, and total procedure time. Results The incidence of adverse events was not significantly different between the groups (EPLBD alone vs. EPLBD with EST: overall adverse events 6% vs. 4%, P =0.75; pancreatitis 1% vs. 3%, P =0.62). Overall success (P =0.35), initial success (P =0.28), and the need for mechanical lithotripsy (P =0.39) were also similar between groups. Median total procedure time tended to be greater in the EPLBD alone group (20.5 minutes) than in the EPLBD with EST group (18 minutes; P =0.08). Conclusion The therapeutic outcomes and adverse events of EPLBD alone for the removal of large bile duct stones were comparable to those of EPLBD with EST.

Original languageEnglish
Pages (from-to)125-132
Number of pages8
JournalEndoscopy
Volume51
Issue number2
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Endoscopic Sphincterotomy
Bile Ducts
Dilatation
Therapeutics
Lithotripsy
Common Bile Duct
Pancreatitis
Multicenter Studies

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Park, Jin Seok ; Jeong, Seok ; Lee, DongKi ; Jang, Sung Ill ; Lee, Tae Hoon ; Park, Sang Heum ; Hwang, Jae Chul ; Kim, Jin Hong ; Yoo, Byoung Moo ; Park, Shin Goo ; Lee, Don Haeng. / Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones. In: Endoscopy. 2019 ; Vol. 51, No. 2. pp. 125-132.
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title = "Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones",
abstract = "Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of large common bile duct (CBD) stones. However, it remains unclear how the outcomes of EPLBD alone compare with those of EPLBD with EST. In this study, we assessed the safety and therapeutic outcomes of EPLBD with vs. without EST for the removal of large bile duct stones. Methods This prospective, multicenter study was conducted on 200 patients with bile duct stones of ≥10mm in diameter. Patients were randomly assigned to an EPLBD alone group (n=100) or an EPLBD with EST group (n=100). These two groups were compared with respect to overall procedure-related adverse events, overall stone removal success rate, number of endoscopic sessions required for complete stone removal, need for mechanical lithotripsy, and total procedure time. Results The incidence of adverse events was not significantly different between the groups (EPLBD alone vs. EPLBD with EST: overall adverse events 6{\%} vs. 4{\%}, P =0.75; pancreatitis 1{\%} vs. 3{\%}, P =0.62). Overall success (P =0.35), initial success (P =0.28), and the need for mechanical lithotripsy (P =0.39) were also similar between groups. Median total procedure time tended to be greater in the EPLBD alone group (20.5 minutes) than in the EPLBD with EST group (18 minutes; P =0.08). Conclusion The therapeutic outcomes and adverse events of EPLBD alone for the removal of large bile duct stones were comparable to those of EPLBD with EST.",
author = "Park, {Jin Seok} and Seok Jeong and DongKi Lee and Jang, {Sung Ill} and Lee, {Tae Hoon} and Park, {Sang Heum} and Hwang, {Jae Chul} and Kim, {Jin Hong} and Yoo, {Byoung Moo} and Park, {Shin Goo} and Lee, {Don Haeng}",
year = "2019",
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Park, JS, Jeong, S, Lee, D, Jang, SI, Lee, TH, Park, SH, Hwang, JC, Kim, JH, Yoo, BM, Park, SG & Lee, DH 2019, 'Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones', Endoscopy, vol. 51, no. 2, pp. 125-132. https://doi.org/10.1055/a-0639-5147

Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones. / Park, Jin Seok; Jeong, Seok; Lee, DongKi; Jang, Sung Ill; Lee, Tae Hoon; Park, Sang Heum; Hwang, Jae Chul; Kim, Jin Hong; Yoo, Byoung Moo; Park, Shin Goo; Lee, Don Haeng.

In: Endoscopy, Vol. 51, No. 2, 01.01.2019, p. 125-132.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of endoscopic papillary large balloon dilation with or without endoscopic sphincterotomy for the treatment of large bile duct stones

AU - Park, Jin Seok

AU - Jeong, Seok

AU - Lee, DongKi

AU - Jang, Sung Ill

AU - Lee, Tae Hoon

AU - Park, Sang Heum

AU - Hwang, Jae Chul

AU - Kim, Jin Hong

AU - Yoo, Byoung Moo

AU - Park, Shin Goo

AU - Lee, Don Haeng

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of large common bile duct (CBD) stones. However, it remains unclear how the outcomes of EPLBD alone compare with those of EPLBD with EST. In this study, we assessed the safety and therapeutic outcomes of EPLBD with vs. without EST for the removal of large bile duct stones. Methods This prospective, multicenter study was conducted on 200 patients with bile duct stones of ≥10mm in diameter. Patients were randomly assigned to an EPLBD alone group (n=100) or an EPLBD with EST group (n=100). These two groups were compared with respect to overall procedure-related adverse events, overall stone removal success rate, number of endoscopic sessions required for complete stone removal, need for mechanical lithotripsy, and total procedure time. Results The incidence of adverse events was not significantly different between the groups (EPLBD alone vs. EPLBD with EST: overall adverse events 6% vs. 4%, P =0.75; pancreatitis 1% vs. 3%, P =0.62). Overall success (P =0.35), initial success (P =0.28), and the need for mechanical lithotripsy (P =0.39) were also similar between groups. Median total procedure time tended to be greater in the EPLBD alone group (20.5 minutes) than in the EPLBD with EST group (18 minutes; P =0.08). Conclusion The therapeutic outcomes and adverse events of EPLBD alone for the removal of large bile duct stones were comparable to those of EPLBD with EST.

AB - Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of large common bile duct (CBD) stones. However, it remains unclear how the outcomes of EPLBD alone compare with those of EPLBD with EST. In this study, we assessed the safety and therapeutic outcomes of EPLBD with vs. without EST for the removal of large bile duct stones. Methods This prospective, multicenter study was conducted on 200 patients with bile duct stones of ≥10mm in diameter. Patients were randomly assigned to an EPLBD alone group (n=100) or an EPLBD with EST group (n=100). These two groups were compared with respect to overall procedure-related adverse events, overall stone removal success rate, number of endoscopic sessions required for complete stone removal, need for mechanical lithotripsy, and total procedure time. Results The incidence of adverse events was not significantly different between the groups (EPLBD alone vs. EPLBD with EST: overall adverse events 6% vs. 4%, P =0.75; pancreatitis 1% vs. 3%, P =0.62). Overall success (P =0.35), initial success (P =0.28), and the need for mechanical lithotripsy (P =0.39) were also similar between groups. Median total procedure time tended to be greater in the EPLBD alone group (20.5 minutes) than in the EPLBD with EST group (18 minutes; P =0.08). Conclusion The therapeutic outcomes and adverse events of EPLBD alone for the removal of large bile duct stones were comparable to those of EPLBD with EST.

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