Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma: A Korean multicenter experience

Hongzoo Park, Seok Soo Byun, Hyeon Hoe Kim, Seung Bae Lee, Tae Gyun Kwon, Seung Hyun Jeon, Seok Ho Kang, Seong Il Seo, Tae Hee Oh, Youn Soo Jeon, Wan Lee, Tae Kon Hwang, KoonHo Rha, Ill Young Seo, Dong Deuk Kwon, Yong June Kim, Yunhee Choi, Sue Kyung Park

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Abstract

Purpose: We analyzed a series of patients who had undergone laparoscopic partial nephrectomies (LPNs) and open partial nephrectomies (OPNs) to compare outcomes of the two procedures in patients with pathologic T1a renal cell carcinomas (RCCs). Materials and Methods: From January 1998 to May 2009, 417 LPNs and 345 OPNs were performed on patients with small renal tumors in 15 institutions in Korea. Of the patients, 273 and 279 patients, respectively, were confirmed to have pT1a RCC. The cohorts were compared with respect to demographics, peri-operative data, and oncologic and functional outcomes. Results: The demographic data were similar between the groups. Although the tumor location was more exophytic (51% vs. 44%, p=0.047) and smaller (2.1 cm vs. 2.3 cm, p=0.026) in the LPN cohort, the OPN cohort demonstrated shorter ischemia times (23.4 min vs. 33.3 min, p<0.001). The LPN cohort was associated with less blood loss than the OPN cohort (293 ml vs. 418 ml, p<0.001). Of note, two patients who underwent LPNs had open conversions and nephrectomies were performed because of intra-operative hemorrhage. The decline in the glomerular filtration rate at the last available follow-up (LPN, 10.9%; and OPN, 10.6%) was similar in both groups (p=0.8). Kaplan-Meier estimates of 5-year local recurrence-free survival (RFS) were 96% after LPN and 94% after OPN (p=0.8). Conclusions: The LPN group demonstrated similar rates of recurrence-free survival, complications, and postoperative GFR change compared with OPN group. The LPN may be an acceptable surgical option in patients with small RCC in Korea.

Original languageEnglish
Pages (from-to)467-471
Number of pages5
JournalKorean Journal of Urology
Volume51
Issue number7
DOIs
Publication statusPublished - 2010 Jul 1

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Nephrectomy
Renal Cell Carcinoma
Korea
Demography
Recurrence
Small Cell Carcinoma
Survival
Kaplan-Meier Estimate
Glomerular Filtration Rate

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Park, Hongzoo ; Byun, Seok Soo ; Kim, Hyeon Hoe ; Lee, Seung Bae ; Kwon, Tae Gyun ; Jeon, Seung Hyun ; Kang, Seok Ho ; Seo, Seong Il ; Oh, Tae Hee ; Jeon, Youn Soo ; Lee, Wan ; Hwang, Tae Kon ; Rha, KoonHo ; Seo, Ill Young ; Kwon, Dong Deuk ; Kim, Yong June ; Choi, Yunhee ; Park, Sue Kyung. / Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma : A Korean multicenter experience. In: Korean Journal of Urology. 2010 ; Vol. 51, No. 7. pp. 467-471.
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title = "Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma: A Korean multicenter experience",
abstract = "Purpose: We analyzed a series of patients who had undergone laparoscopic partial nephrectomies (LPNs) and open partial nephrectomies (OPNs) to compare outcomes of the two procedures in patients with pathologic T1a renal cell carcinomas (RCCs). Materials and Methods: From January 1998 to May 2009, 417 LPNs and 345 OPNs were performed on patients with small renal tumors in 15 institutions in Korea. Of the patients, 273 and 279 patients, respectively, were confirmed to have pT1a RCC. The cohorts were compared with respect to demographics, peri-operative data, and oncologic and functional outcomes. Results: The demographic data were similar between the groups. Although the tumor location was more exophytic (51{\%} vs. 44{\%}, p=0.047) and smaller (2.1 cm vs. 2.3 cm, p=0.026) in the LPN cohort, the OPN cohort demonstrated shorter ischemia times (23.4 min vs. 33.3 min, p<0.001). The LPN cohort was associated with less blood loss than the OPN cohort (293 ml vs. 418 ml, p<0.001). Of note, two patients who underwent LPNs had open conversions and nephrectomies were performed because of intra-operative hemorrhage. The decline in the glomerular filtration rate at the last available follow-up (LPN, 10.9{\%}; and OPN, 10.6{\%}) was similar in both groups (p=0.8). Kaplan-Meier estimates of 5-year local recurrence-free survival (RFS) were 96{\%} after LPN and 94{\%} after OPN (p=0.8). Conclusions: The LPN group demonstrated similar rates of recurrence-free survival, complications, and postoperative GFR change compared with OPN group. The LPN may be an acceptable surgical option in patients with small RCC in Korea.",
author = "Hongzoo Park and Byun, {Seok Soo} and Kim, {Hyeon Hoe} and Lee, {Seung Bae} and Kwon, {Tae Gyun} and Jeon, {Seung Hyun} and Kang, {Seok Ho} and Seo, {Seong Il} and Oh, {Tae Hee} and Jeon, {Youn Soo} and Wan Lee and Hwang, {Tae Kon} and KoonHo Rha and Seo, {Ill Young} and Kwon, {Dong Deuk} and Kim, {Yong June} and Yunhee Choi and Park, {Sue Kyung}",
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Park, H, Byun, SS, Kim, HH, Lee, SB, Kwon, TG, Jeon, SH, Kang, SH, Seo, SI, Oh, TH, Jeon, YS, Lee, W, Hwang, TK, Rha, K, Seo, IY, Kwon, DD, Kim, YJ, Choi, Y & Park, SK 2010, 'Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma: A Korean multicenter experience', Korean Journal of Urology, vol. 51, no. 7, pp. 467-471. https://doi.org/10.4111/kju.2010.51.7.467

Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma : A Korean multicenter experience. / Park, Hongzoo; Byun, Seok Soo; Kim, Hyeon Hoe; Lee, Seung Bae; Kwon, Tae Gyun; Jeon, Seung Hyun; Kang, Seok Ho; Seo, Seong Il; Oh, Tae Hee; Jeon, Youn Soo; Lee, Wan; Hwang, Tae Kon; Rha, KoonHo; Seo, Ill Young; Kwon, Dong Deuk; Kim, Yong June; Choi, Yunhee; Park, Sue Kyung.

In: Korean Journal of Urology, Vol. 51, No. 7, 01.07.2010, p. 467-471.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of laparoscopic and open partial nephrectomies in T1a renal cell carcinoma

T2 - A Korean multicenter experience

AU - Park, Hongzoo

AU - Byun, Seok Soo

AU - Kim, Hyeon Hoe

AU - Lee, Seung Bae

AU - Kwon, Tae Gyun

AU - Jeon, Seung Hyun

AU - Kang, Seok Ho

AU - Seo, Seong Il

AU - Oh, Tae Hee

AU - Jeon, Youn Soo

AU - Lee, Wan

AU - Hwang, Tae Kon

AU - Rha, KoonHo

AU - Seo, Ill Young

AU - Kwon, Dong Deuk

AU - Kim, Yong June

AU - Choi, Yunhee

AU - Park, Sue Kyung

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Purpose: We analyzed a series of patients who had undergone laparoscopic partial nephrectomies (LPNs) and open partial nephrectomies (OPNs) to compare outcomes of the two procedures in patients with pathologic T1a renal cell carcinomas (RCCs). Materials and Methods: From January 1998 to May 2009, 417 LPNs and 345 OPNs were performed on patients with small renal tumors in 15 institutions in Korea. Of the patients, 273 and 279 patients, respectively, were confirmed to have pT1a RCC. The cohorts were compared with respect to demographics, peri-operative data, and oncologic and functional outcomes. Results: The demographic data were similar between the groups. Although the tumor location was more exophytic (51% vs. 44%, p=0.047) and smaller (2.1 cm vs. 2.3 cm, p=0.026) in the LPN cohort, the OPN cohort demonstrated shorter ischemia times (23.4 min vs. 33.3 min, p<0.001). The LPN cohort was associated with less blood loss than the OPN cohort (293 ml vs. 418 ml, p<0.001). Of note, two patients who underwent LPNs had open conversions and nephrectomies were performed because of intra-operative hemorrhage. The decline in the glomerular filtration rate at the last available follow-up (LPN, 10.9%; and OPN, 10.6%) was similar in both groups (p=0.8). Kaplan-Meier estimates of 5-year local recurrence-free survival (RFS) were 96% after LPN and 94% after OPN (p=0.8). Conclusions: The LPN group demonstrated similar rates of recurrence-free survival, complications, and postoperative GFR change compared with OPN group. The LPN may be an acceptable surgical option in patients with small RCC in Korea.

AB - Purpose: We analyzed a series of patients who had undergone laparoscopic partial nephrectomies (LPNs) and open partial nephrectomies (OPNs) to compare outcomes of the two procedures in patients with pathologic T1a renal cell carcinomas (RCCs). Materials and Methods: From January 1998 to May 2009, 417 LPNs and 345 OPNs were performed on patients with small renal tumors in 15 institutions in Korea. Of the patients, 273 and 279 patients, respectively, were confirmed to have pT1a RCC. The cohorts were compared with respect to demographics, peri-operative data, and oncologic and functional outcomes. Results: The demographic data were similar between the groups. Although the tumor location was more exophytic (51% vs. 44%, p=0.047) and smaller (2.1 cm vs. 2.3 cm, p=0.026) in the LPN cohort, the OPN cohort demonstrated shorter ischemia times (23.4 min vs. 33.3 min, p<0.001). The LPN cohort was associated with less blood loss than the OPN cohort (293 ml vs. 418 ml, p<0.001). Of note, two patients who underwent LPNs had open conversions and nephrectomies were performed because of intra-operative hemorrhage. The decline in the glomerular filtration rate at the last available follow-up (LPN, 10.9%; and OPN, 10.6%) was similar in both groups (p=0.8). Kaplan-Meier estimates of 5-year local recurrence-free survival (RFS) were 96% after LPN and 94% after OPN (p=0.8). Conclusions: The LPN group demonstrated similar rates of recurrence-free survival, complications, and postoperative GFR change compared with OPN group. The LPN may be an acceptable surgical option in patients with small RCC in Korea.

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