Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia

Jae Bum Lee, Gong Je Seong, Jong Hyuck Lee, KyoungYul Seo, Young Ghee Lee, Eungkweon Kim

Research output: Contribution to journalArticle

204 Citations (Scopus)

Abstract

Purpose: To compare the effectiveness, safety, and stability of laser epithelial keratomileusis (LASEK), a modified photorefractive keratectomy (PRK) technique, with those of conventional PRK for low to moderate myopia. Setting: Department of Ophthalmology, Yonsei University School of Medicine, Seoul, Korea. Methods: In this prospective study, 27 patients with a manifest refraction of -3.00 to -6.50 diopters were treated and followed for 3 months. In each case, PRK was performed in 1 eye and LASEK in the other eye. The first eye treated and the surgical method used in the first eye were randomized. Postoperative pain, epithelial healing time, uncorrected visual acuity (UCVA), manifest refraction, corneal haze, and surgical preference were examined in PRK- and LASEK-treated eyes. Results: During the 3 month follow-up, there were no significant between-eye differences in epithelial healing time, UCVA, or refractive error. However, LASEK-treated eyes had lower postoperative pain scores (P = .047) and corneal haze scores (1 month; P = .02) than PRK-treated eyes. Seventeen patients (63%) preferred the LASEK procedure. Conclusions: Laser epithelial keratomileusis safely and effectively treated eyes with low to moderate myopia. It reduced the incidence of significant postoperative pain and corneal haze and may prevent the flap- and interface-related problems of laser in situ keratomileusis.

Original languageEnglish
Pages (from-to)565-570
Number of pages6
JournalJournal of Cataract and Refractive Surgery
Volume27
Issue number4
DOIs
Publication statusPublished - 2001 Apr 1

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Photorefractive Keratectomy
Myopia
Lasers
Postoperative Pain
Visual Acuity
Laser In Situ Keratomileusis
Refractive Errors
Ophthalmology
Korea
Medicine
Prospective Studies
Safety

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology
  • Sensory Systems

Cite this

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title = "Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia",
abstract = "Purpose: To compare the effectiveness, safety, and stability of laser epithelial keratomileusis (LASEK), a modified photorefractive keratectomy (PRK) technique, with those of conventional PRK for low to moderate myopia. Setting: Department of Ophthalmology, Yonsei University School of Medicine, Seoul, Korea. Methods: In this prospective study, 27 patients with a manifest refraction of -3.00 to -6.50 diopters were treated and followed for 3 months. In each case, PRK was performed in 1 eye and LASEK in the other eye. The first eye treated and the surgical method used in the first eye were randomized. Postoperative pain, epithelial healing time, uncorrected visual acuity (UCVA), manifest refraction, corneal haze, and surgical preference were examined in PRK- and LASEK-treated eyes. Results: During the 3 month follow-up, there were no significant between-eye differences in epithelial healing time, UCVA, or refractive error. However, LASEK-treated eyes had lower postoperative pain scores (P = .047) and corneal haze scores (1 month; P = .02) than PRK-treated eyes. Seventeen patients (63{\%}) preferred the LASEK procedure. Conclusions: Laser epithelial keratomileusis safely and effectively treated eyes with low to moderate myopia. It reduced the incidence of significant postoperative pain and corneal haze and may prevent the flap- and interface-related problems of laser in situ keratomileusis.",
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Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia. / Lee, Jae Bum; Seong, Gong Je; Lee, Jong Hyuck; Seo, KyoungYul; Lee, Young Ghee; Kim, Eungkweon.

In: Journal of Cataract and Refractive Surgery, Vol. 27, No. 4, 01.04.2001, p. 565-570.

Research output: Contribution to journalArticle

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T1 - Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia

AU - Lee, Jae Bum

AU - Seong, Gong Je

AU - Lee, Jong Hyuck

AU - Seo, KyoungYul

AU - Lee, Young Ghee

AU - Kim, Eungkweon

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N2 - Purpose: To compare the effectiveness, safety, and stability of laser epithelial keratomileusis (LASEK), a modified photorefractive keratectomy (PRK) technique, with those of conventional PRK for low to moderate myopia. Setting: Department of Ophthalmology, Yonsei University School of Medicine, Seoul, Korea. Methods: In this prospective study, 27 patients with a manifest refraction of -3.00 to -6.50 diopters were treated and followed for 3 months. In each case, PRK was performed in 1 eye and LASEK in the other eye. The first eye treated and the surgical method used in the first eye were randomized. Postoperative pain, epithelial healing time, uncorrected visual acuity (UCVA), manifest refraction, corneal haze, and surgical preference were examined in PRK- and LASEK-treated eyes. Results: During the 3 month follow-up, there were no significant between-eye differences in epithelial healing time, UCVA, or refractive error. However, LASEK-treated eyes had lower postoperative pain scores (P = .047) and corneal haze scores (1 month; P = .02) than PRK-treated eyes. Seventeen patients (63%) preferred the LASEK procedure. Conclusions: Laser epithelial keratomileusis safely and effectively treated eyes with low to moderate myopia. It reduced the incidence of significant postoperative pain and corneal haze and may prevent the flap- and interface-related problems of laser in situ keratomileusis.

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