Comparison of long-term (over 10 years) outcome of percutaneous mitral balloon valvuloplotomy between moderate and severe mitral stenosis

Jung Sun Kim, Boyoung Joung, Seok Min Kang, Jong Won Ha, Young Guk Ko, Donghoon Choi, Yangsoo Jang, Namsik Chung, Won Heum Shim, Seung Yun Cho, Sung Soon Kim, Changsoo Kim, Jung Mo Nam

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Background and Objectives: Percutaneous mitral balloon valvuloplotomy (PMV) is a safe and effective procedure for the treatment of mitral stenosis (MS); however, its long-term results according to the severity of MS remain unknown. The aim of this study was to compare the long-term results of PMV between moderate and severe MS. Subjects and Methods: The immediate and long-term outcomes of 786 patients (198 male, mean age; 43 years) who underwent PMV at a single referral center, between 1988 and 2000, were analyzed. The clinical and echocardiographic data were compared between moderate (n=357) and severe MS (n=429). Results: Optimal results were gained in 618 (79%) patients, including 80 and 76% moderate and severe MS cases, respectively (p=0.13). Acute complications occurred in 85 patients (11%), but without significant difference between the two groups. After a mean follow-up period of 94 months (range, 6 to 210 month), the 5 year event-free survival rate was better in moderate (88%) than in severe MS (79%), but the 10 year event-free survival rates were no different (65% vs. 65%). Independent predictors for better prognosis were a lower echo score (≤8) (p=0.017, HR=0.67), a larger mitral valve area after the PMV (≥1.7 cm2) (p=0.002, HR=0.65), less mitral regurgitation (<grade III) (p=0.001, HR=0.46) and a lower left atrial pressure (<12 mmHg) (p=0.005, HR=0.80). Conclusion: The immediate and long-term outcomes of PMV for moderate MS were no better after 9 years than those for severe MS. Therefore, PMV for moderate MS should be considered in selected cases with a favorable MV morphology.

Original languageEnglish
Pages (from-to)208-213
Number of pages6
JournalKorean Circulation Journal
Issue number3
Publication statusPublished - 2006 Mar

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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