Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis

Sang Hyeon Ahn, Eun Jung Lee, Jong Gyun Ha, Chi Sang Hwang, Joo Heon Yoon, Chang Hoon Kim, Hyung Ju Cho

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1 Citation (Scopus)

Abstract

Objective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS), have not been clearly reported. Therefore, the purpose of this study was to investigate the clinical features in olfactory and taste functions according to the subtype classified as ECRS and NCRS. Methods: We retrospectively analyzed the electronic medical records of patients who underwent endoscopic sinus surgery and were diagnosed with CRS. The patients were divided into ECRS and NCRS groups, according to their Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) scores. We analyzed demographic characteristics, Sino-Nasal Outcome Test findings, Lund-Mackay score, and the results of previously-validated tests, including the Korean Version of Sniffin' Stick test and chemical gustatory function test. Results: Patients with ECRS and NCRS had decreased olfactory and taste functions compared to the control group. In particular, the olfactory score of ECRS patients was lower than that of NCRS patients (18.1 ± 9.5 vs 23.7 ± 8.5, respectively, p <0.001). On the other hand, taste scores of ECRS patients were not statistically different compared to NCRS patients (19.1 ± 4.7 vs. 18.3 ± 4.7, respectively, p = 0.166). Olfactory score decreased with increase in JESREC score (r=-0.203, p = 0.002), but it had no correlation with taste score (r = 0.072, p = 0.276). Conclusion: We found a difference in olfactory function but no difference in taste function between patients in ECRS and NCRS groups. These results may provide valuable clinical features in terms of olfactory and taste functions according to the subtypes of CRS.

Original languageEnglish
Pages (from-to)820-827
Number of pages8
JournalAuris Nasus Larynx
Volume47
Issue number5
DOIs
Publication statusPublished - 2020 Oct

Bibliographical note

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2018R1D1A1A02049236) to H.J. Cho. This study was supported by a Faculty Research Grant of Yonsei University College of Medicine to H.J. Cho (6-2018-0167). This work was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (No.2016R1A5A2008630). This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2016M3A9D5A01952414). This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2020R1C1C1007727) to S.H. Ahn.

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea ( NRF ) funded by the Ministry of Education ( NRF-2018R1D1A1A02049236 ) to H.J. Cho. This study was supported by a Faculty Research Grant of Yonsei University College of Medicine to H.J. Cho ( 6-2018-0167 ). This work was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government ( MSIP ) (No. 2016R1A5A2008630 ). This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation ( NRF ) funded by the Ministry of Science, ICT & Future Planning ( NRF-2016M3A9D5A01952414 ). This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government ( MSIT ) (No. 2020R1C1C1007727 ) to S.H. Ahn.

Publisher Copyright:
© 2020

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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