Comparison of Outcomes between Combined Transepithelial Photorefractive Keratectomy with and Without Accelerated Corneal Collagen Cross-Linking

A 1-Year Study

Hun Lee, David Sung Yong Kang, Byoung Jin Ha, Jin Young Choi, Eungkweon Kim, KyoungYul Seo, Tae-im Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To investigate the effects of combined transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) on visual acuity and refractive outcomes. Methods: The medical records of 89 eyes (89 patients) undergoing combined tPRK and CXL (tPRK-CXL group) or tPRK alone (tPRK group) were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, and manifest refraction spherical equivalent (MRSE) were evaluated preoperatively and 2 weeks, 1, 3, 6, and 12 months after surgery. Results: At 2 weeks after surgery, the tPRK-CXL group had better UDVA than the tPRK group (0.97 ± 0.22 vs. 0.85 ± 0.22, P = 0.015). At 2 weeks and 1 month after surgery, the tPRK-CXL group had a significantly lower spherical error than the tPRK group (0.24 vs. 0.63 D, P = 0.017, for 2 weeks and 0.43 vs. 0.57 D, P = 0.019, for 1 month). At 12 months after surgery, the tPRK-CXL group had a lower spherical error and MRSE than the tPRK group (0.30 vs. 0.44 D, P < 0.001, for the spherical error and 0.17 vs. 0.31 D, P < 0.001, for the MRSE). Both groups had comparable predictability, efficacy, and safety indices at 12 months after surgery. Conclusions: Combined tPRK and accelerated CXL demonstrated comparable predictability, efficacy, and safety compared with tPRK alone. Combined tPRK and CXL provides better UDVA in the early postoperative period and better refractive outcomes at 12 months postoperatively in terms of spherical error and MRSE.

Original languageEnglish
Pages (from-to)1213-1220
Number of pages8
JournalCornea
Volume36
Issue number10
DOIs
Publication statusPublished - 2017 Oct 1

Fingerprint

Photorefractive Keratectomy
Collagen
Visual Acuity
Safety
Postoperative Period

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

@article{edc337e9edec44af86e2dc5e96b62453,
title = "Comparison of Outcomes between Combined Transepithelial Photorefractive Keratectomy with and Without Accelerated Corneal Collagen Cross-Linking: A 1-Year Study",
abstract = "Purpose: To investigate the effects of combined transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) on visual acuity and refractive outcomes. Methods: The medical records of 89 eyes (89 patients) undergoing combined tPRK and CXL (tPRK-CXL group) or tPRK alone (tPRK group) were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, and manifest refraction spherical equivalent (MRSE) were evaluated preoperatively and 2 weeks, 1, 3, 6, and 12 months after surgery. Results: At 2 weeks after surgery, the tPRK-CXL group had better UDVA than the tPRK group (0.97 ± 0.22 vs. 0.85 ± 0.22, P = 0.015). At 2 weeks and 1 month after surgery, the tPRK-CXL group had a significantly lower spherical error than the tPRK group (0.24 vs. 0.63 D, P = 0.017, for 2 weeks and 0.43 vs. 0.57 D, P = 0.019, for 1 month). At 12 months after surgery, the tPRK-CXL group had a lower spherical error and MRSE than the tPRK group (0.30 vs. 0.44 D, P < 0.001, for the spherical error and 0.17 vs. 0.31 D, P < 0.001, for the MRSE). Both groups had comparable predictability, efficacy, and safety indices at 12 months after surgery. Conclusions: Combined tPRK and accelerated CXL demonstrated comparable predictability, efficacy, and safety compared with tPRK alone. Combined tPRK and CXL provides better UDVA in the early postoperative period and better refractive outcomes at 12 months postoperatively in terms of spherical error and MRSE.",
author = "Hun Lee and {Yong Kang}, {David Sung} and Ha, {Byoung Jin} and Choi, {Jin Young} and Eungkweon Kim and KyoungYul Seo and Tae-im Kim",
year = "2017",
month = "10",
day = "1",
doi = "10.1097/ICO.0000000000001308",
language = "English",
volume = "36",
pages = "1213--1220",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

Comparison of Outcomes between Combined Transepithelial Photorefractive Keratectomy with and Without Accelerated Corneal Collagen Cross-Linking : A 1-Year Study. / Lee, Hun; Yong Kang, David Sung; Ha, Byoung Jin; Choi, Jin Young; Kim, Eungkweon; Seo, KyoungYul; Kim, Tae-im.

In: Cornea, Vol. 36, No. 10, 01.10.2017, p. 1213-1220.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of Outcomes between Combined Transepithelial Photorefractive Keratectomy with and Without Accelerated Corneal Collagen Cross-Linking

T2 - A 1-Year Study

AU - Lee, Hun

AU - Yong Kang, David Sung

AU - Ha, Byoung Jin

AU - Choi, Jin Young

AU - Kim, Eungkweon

AU - Seo, KyoungYul

AU - Kim, Tae-im

PY - 2017/10/1

Y1 - 2017/10/1

N2 - Purpose: To investigate the effects of combined transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) on visual acuity and refractive outcomes. Methods: The medical records of 89 eyes (89 patients) undergoing combined tPRK and CXL (tPRK-CXL group) or tPRK alone (tPRK group) were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, and manifest refraction spherical equivalent (MRSE) were evaluated preoperatively and 2 weeks, 1, 3, 6, and 12 months after surgery. Results: At 2 weeks after surgery, the tPRK-CXL group had better UDVA than the tPRK group (0.97 ± 0.22 vs. 0.85 ± 0.22, P = 0.015). At 2 weeks and 1 month after surgery, the tPRK-CXL group had a significantly lower spherical error than the tPRK group (0.24 vs. 0.63 D, P = 0.017, for 2 weeks and 0.43 vs. 0.57 D, P = 0.019, for 1 month). At 12 months after surgery, the tPRK-CXL group had a lower spherical error and MRSE than the tPRK group (0.30 vs. 0.44 D, P < 0.001, for the spherical error and 0.17 vs. 0.31 D, P < 0.001, for the MRSE). Both groups had comparable predictability, efficacy, and safety indices at 12 months after surgery. Conclusions: Combined tPRK and accelerated CXL demonstrated comparable predictability, efficacy, and safety compared with tPRK alone. Combined tPRK and CXL provides better UDVA in the early postoperative period and better refractive outcomes at 12 months postoperatively in terms of spherical error and MRSE.

AB - Purpose: To investigate the effects of combined transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) on visual acuity and refractive outcomes. Methods: The medical records of 89 eyes (89 patients) undergoing combined tPRK and CXL (tPRK-CXL group) or tPRK alone (tPRK group) were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, and manifest refraction spherical equivalent (MRSE) were evaluated preoperatively and 2 weeks, 1, 3, 6, and 12 months after surgery. Results: At 2 weeks after surgery, the tPRK-CXL group had better UDVA than the tPRK group (0.97 ± 0.22 vs. 0.85 ± 0.22, P = 0.015). At 2 weeks and 1 month after surgery, the tPRK-CXL group had a significantly lower spherical error than the tPRK group (0.24 vs. 0.63 D, P = 0.017, for 2 weeks and 0.43 vs. 0.57 D, P = 0.019, for 1 month). At 12 months after surgery, the tPRK-CXL group had a lower spherical error and MRSE than the tPRK group (0.30 vs. 0.44 D, P < 0.001, for the spherical error and 0.17 vs. 0.31 D, P < 0.001, for the MRSE). Both groups had comparable predictability, efficacy, and safety indices at 12 months after surgery. Conclusions: Combined tPRK and accelerated CXL demonstrated comparable predictability, efficacy, and safety compared with tPRK alone. Combined tPRK and CXL provides better UDVA in the early postoperative period and better refractive outcomes at 12 months postoperatively in terms of spherical error and MRSE.

UR - http://www.scopus.com/inward/record.url?scp=85026353452&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026353452&partnerID=8YFLogxK

U2 - 10.1097/ICO.0000000000001308

DO - 10.1097/ICO.0000000000001308

M3 - Article

VL - 36

SP - 1213

EP - 1220

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 10

ER -