Comparison of quantitative angiographic parameters with the magnitude of neointimal hyperplasia measured by volumetric intravascular ultrasound in patients treated with bare metal and nonpolymeric paclitaxel-coated stents

Gary S. Mintz, Myeong Ki Hong, Albert E. Raizner, Cheol Whan Lee, Jae Joong Kim, Esteban Escolar, Neal E. Fearnot, Seong Wook Park, Seung Jung Park, Neil J. Weissman

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We used data from the ASian Paclitaxel-Eluting Stent Clinical Trial (a 3-center, randomized, placebo-controlled trial of nonpolymeric paclitaxel-coated stents with a single-center intravascular ultrasound substudy) to compare angiographic indexes of drug-eluting stent efficacy with the magnitude of intimal hyperplasia (IH) assessed by intravascular ultrasound. Overall, percent IH (IH volume divided by stent volume) was larger in restenotic lesions than in nonrestenotic lesions (46 ± 19% vs 15 ± 13%, p <0.0001); angiographic late loss and follow-up diameter stenoses correlated strongly with percent IH.

Original languageEnglish
Pages (from-to)105-107
Number of pages3
JournalAmerican Journal of Cardiology
Volume95
Issue number1
DOIs
Publication statusPublished - 2005 Jan 1

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Tunica Intima
Paclitaxel
Hyperplasia
Stents
Metals
Drug-Eluting Stents
Pathologic Constriction
Randomized Controlled Trials
Placebos
Clinical Trials

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Mintz, Gary S. ; Hong, Myeong Ki ; Raizner, Albert E. ; Lee, Cheol Whan ; Kim, Jae Joong ; Escolar, Esteban ; Fearnot, Neal E. ; Park, Seong Wook ; Park, Seung Jung ; Weissman, Neil J. / Comparison of quantitative angiographic parameters with the magnitude of neointimal hyperplasia measured by volumetric intravascular ultrasound in patients treated with bare metal and nonpolymeric paclitaxel-coated stents. In: American Journal of Cardiology. 2005 ; Vol. 95, No. 1. pp. 105-107.
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Comparison of quantitative angiographic parameters with the magnitude of neointimal hyperplasia measured by volumetric intravascular ultrasound in patients treated with bare metal and nonpolymeric paclitaxel-coated stents. / Mintz, Gary S.; Hong, Myeong Ki; Raizner, Albert E.; Lee, Cheol Whan; Kim, Jae Joong; Escolar, Esteban; Fearnot, Neal E.; Park, Seong Wook; Park, Seung Jung; Weissman, Neil J.

In: American Journal of Cardiology, Vol. 95, No. 1, 01.01.2005, p. 105-107.

Research output: Contribution to journalArticle

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