Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia

Seung Hun Lee, Myung Ho Jeong, Kyoo Rok Han, Doo Sun Sim, Junghan Yoon, Youngjin Youn, Byung Ryeol Cho, Kwang Soo Cha, Min Su Hyon, Seung Woon Rha, Byung Ok Kim, Won Yong Shin, Keum Soo Park, Sang Sig Cheong

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed periprocedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dl for men and <12 g/dl for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 patients (72.7%) underwent TRI and 95 patients (27.3%) underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs TFI 12.6%, p = 0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications (hazard ratio 0.34, 95% CI 0.12 to 0.99, p = 0.049) and lower incidence of in-hospital mortality than TFI group (hazard ratio 0.74, 95% CI 0.62 to 0.88, p = 0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.

Original languageEnglish
Pages (from-to)1582-1587
Number of pages6
JournalAmerican Journal of Cardiology
Volume117
Issue number10
DOIs
Publication statusPublished - 2016 May 15

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Percutaneous Coronary Intervention
Acute Coronary Syndrome
Anemia
Hospital Mortality
Hemorrhage
Incidence
Dyslipidemias
Chronic Renal Insufficiency
Registries
Hemoglobins
Logistic Models
Regression Analysis
Demography

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Lee, Seung Hun ; Jeong, Myung Ho ; Han, Kyoo Rok ; Sim, Doo Sun ; Yoon, Junghan ; Youn, Youngjin ; Cho, Byung Ryeol ; Cha, Kwang Soo ; Hyon, Min Su ; Rha, Seung Woon ; Kim, Byung Ok ; Shin, Won Yong ; Park, Keum Soo ; Cheong, Sang Sig. / Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia. In: American Journal of Cardiology. 2016 ; Vol. 117, No. 10. pp. 1582-1587.
@article{369113968e914efa801b19f4e09733bb,
title = "Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia",
abstract = "Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed periprocedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dl for men and <12 g/dl for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 patients (72.7{\%}) underwent TRI and 95 patients (27.3{\%}) underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7{\%} vs TFI 12.6{\%}, p = 0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications (hazard ratio 0.34, 95{\%} CI 0.12 to 0.99, p = 0.049) and lower incidence of in-hospital mortality than TFI group (hazard ratio 0.74, 95{\%} CI 0.62 to 0.88, p = 0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.",
author = "Lee, {Seung Hun} and Jeong, {Myung Ho} and Han, {Kyoo Rok} and Sim, {Doo Sun} and Junghan Yoon and Youngjin Youn and Cho, {Byung Ryeol} and Cha, {Kwang Soo} and Hyon, {Min Su} and Rha, {Seung Woon} and Kim, {Byung Ok} and Shin, {Won Yong} and Park, {Keum Soo} and Cheong, {Sang Sig}",
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Lee, SH, Jeong, MH, Han, KR, Sim, DS, Yoon, J, Youn, Y, Cho, BR, Cha, KS, Hyon, MS, Rha, SW, Kim, BO, Shin, WY, Park, KS & Cheong, SS 2016, 'Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia', American Journal of Cardiology, vol. 117, no. 10, pp. 1582-1587. https://doi.org/10.1016/j.amjcard.2016.02.030

Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia. / Lee, Seung Hun; Jeong, Myung Ho; Han, Kyoo Rok; Sim, Doo Sun; Yoon, Junghan; Youn, Youngjin; Cho, Byung Ryeol; Cha, Kwang Soo; Hyon, Min Su; Rha, Seung Woon; Kim, Byung Ok; Shin, Won Yong; Park, Keum Soo; Cheong, Sang Sig.

In: American Journal of Cardiology, Vol. 117, No. 10, 15.05.2016, p. 1582-1587.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of transradial and transfemoral approaches for percutaneous coronary intervention in patients with acute coronary syndrome and anemia

AU - Lee, Seung Hun

AU - Jeong, Myung Ho

AU - Han, Kyoo Rok

AU - Sim, Doo Sun

AU - Yoon, Junghan

AU - Youn, Youngjin

AU - Cho, Byung Ryeol

AU - Cha, Kwang Soo

AU - Hyon, Min Su

AU - Rha, Seung Woon

AU - Kim, Byung Ok

AU - Shin, Won Yong

AU - Park, Keum Soo

AU - Cheong, Sang Sig

PY - 2016/5/15

Y1 - 2016/5/15

N2 - Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed periprocedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dl for men and <12 g/dl for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 patients (72.7%) underwent TRI and 95 patients (27.3%) underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs TFI 12.6%, p = 0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications (hazard ratio 0.34, 95% CI 0.12 to 0.99, p = 0.049) and lower incidence of in-hospital mortality than TFI group (hazard ratio 0.74, 95% CI 0.62 to 0.88, p = 0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.

AB - Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed periprocedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dl for men and <12 g/dl for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 patients (72.7%) underwent TRI and 95 patients (27.3%) underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs TFI 12.6%, p = 0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications (hazard ratio 0.34, 95% CI 0.12 to 0.99, p = 0.049) and lower incidence of in-hospital mortality than TFI group (hazard ratio 0.74, 95% CI 0.62 to 0.88, p = 0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.

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JO - American Journal of Cardiology

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