Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family

Seung Jung Han, Taeksun Song, Yong Joon Cho, Jong Seok Kim, Soo Young Choi, Hye Eun Bang, Jongsik Chun, Gill Han Bai, Sangnae Cho, SungJae Shin

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Abstract

Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals.

Original languageEnglish
Article number78
JournalStandards in Genomic Sciences
Volume10
Issue number1
DOIs
Publication statusPublished - 2015 Oct 14

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All Science Journal Classification (ASJC) codes

  • Genetics

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