Streptomyces venezuelae ATCC 15439, which produces 12- and 14-membered ring macrolide antibiotics, is a platform strain for heterologous expression of secondary metabolites. Its 9.05-Mb genome sequence revealed an abundance of genes involved in the biosynthesis of secondary metabolites and their precursors, which should be useful for the production of bioactive compounds.
Bibliographical noteFunding Information:
This work was supported by the Global Frontier Intelligent Synthetic Biology Center ( 2011-0031961 to YJY, NRF-2012M3A6A8053632 to JFK, and 2011-0031960 to JHR) and the Strategic Initiative for Microbiomes in Agriculture and Food ( 914006-04-2-HD020 to JYS), Republic of Korea.
© 2015 Elsevier B.V.
All Science Journal Classification (ASJC) codes
- Applied Microbiology and Biotechnology