Complete resolution of posttransplant lymphoproliferative disorder (diffuse large B-cell lymphoma) with reduction of immunosuppressive therapy

Han Jak Ryu, Jee Sook Hahn, Yu Seun Kim, Kiil Park, Woo Ick Yang, Jong Doo Lee

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. PTLD is the disorder arising from the combined effects of Epstein-Barr virus associated lymphoid proliferation with the disruption of the normal immune control by the cytotoxic T cells. The treatment for PTLD is one of the most controversial topics in solid organ transplantation. It is well known that the initial management of PTLD is a reduction of immunosuppression. Early diagnosis and the early reduction in immunosuppression are essential even for monomorphic lymphoma. We report here on a case of the complete resolution of PTLD (diffuse large B cell lymphoma) which occurred after a drastic reduction of immunosuppression in a renal transplant recipient.

Original languageEnglish
Pages (from-to)527-532
Number of pages6
JournalYonsei medical journal
Volume45
Issue number3
DOIs
Publication statusPublished - 2004 Jun 30

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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