Complications After Deep Brain Stimulation: A 21-Year Experience in 426 Patients

In Ho Jung, Kyung Won Chang, So Hee Park, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang

Research output: Contribution to journalArticlepeer-review


Background: Deep brain stimulation is an established treatment for movement disorders such as Parkinson’s disease, essential tremor, and dystonia. However, various complications that occur after deep brain stimulation are a major concern for patients and neurosurgeons. Objective: This study aimed to analyze various complications that occur after deep brain stimulation. Methods: We reviewed the medical records of patients with a movement disorder who underwent bilateral deep brain stimulation between 2000 and 2020. Among them, patients requiring revision surgery were analyzed. Results: A total of 426 patients underwent bilateral deep brain stimulation for a movement disorder. The primary disease was Parkinson’s disease in 315 patients, followed by dystonia in 71 patients and essential tremor in 40 patients. Twenty-six (6.1%) patients had complications requiring revision surgery; the most common complication was infection (12 patients, 2.8%). Conclusion: Various complications may occur after deep brain stimulation, and patient prognosis should be improved by reducing complications.

Original languageEnglish
Article number819730
JournalFrontiers in Aging Neuroscience
Publication statusPublished - 2022 Apr 7

Bibliographical note

Funding Information:
The authors thank Eun Jung Kweon (registered nurse, masters prepared nurses, Korean oncology advanced practice nurse), Sang Keum Pak (registered nurse, masters prepared nurses), and Seung Jun Kim (registered nurse) for their tremendous dedication in the Stereotactic and Functional neurosurgery department of Severance hospital.

Publisher Copyright:
Copyright © 2022 Jung, Chang, Park, Chang, Jung and Chang.

All Science Journal Classification (ASJC) codes

  • Ageing
  • Cognitive Neuroscience


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