Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

Matthew M. Crane, Kwanghun Chung, Hang Lu

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Most visual screens based on fluorescent markers are currently limited in throughput and accuracy. Here we present the first genetic screen of a mutagenized population of C. elegans in a microfluidic device. Animal handling streamlined by a microfluidic device and intuitive control software enabled the identification of novel mutants and a large screening speed.

Original languageEnglish
Pages (from-to)38-40
Number of pages3
JournalLab on a Chip
Volume9
Issue number1
DOIs
Publication statusPublished - 2009 Jan 1

Fingerprint

Lab-On-A-Chip Devices
Microfluidics
Throughput
Screening
Animals
Software
Population

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

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Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system. / Crane, Matthew M.; Chung, Kwanghun; Lu, Hang.

In: Lab on a Chip, Vol. 9, No. 1, 01.01.2009, p. 38-40.

Research output: Contribution to journalArticle

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