Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

Matthew M. Crane, Kwanghun Chung, Hang Lu

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Most visual screens based on fluorescent markers are currently limited in throughput and accuracy. Here we present the first genetic screen of a mutagenized population of C. elegans in a microfluidic device. Animal handling streamlined by a microfluidic device and intuitive control software enabled the identification of novel mutants and a large screening speed.

Original languageEnglish
Pages (from-to)38-40
Number of pages3
JournalLab on a chip
Volume9
Issue number1
DOIs
Publication statusPublished - 2009 Jan 1

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All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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