Concise asymmetric total synthesis of ent -guadinomic acid from an epoxy alkenol

Hyemi Kim, Myung Yeol Kim, Jinsung Tae

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A highly efficient asymmetric total synthesis of ent-guadinomic acid [(-)-K01-0509 B] was accomplished from the known epoxy alkenol which is resolved by HKR method. Cross metathesis of the alkene part with acrylate and epoxide opening with azide followed by intramolecular guanidine formation reactions furnished ent-guadinomic acid.

Original languageEnglish
Pages (from-to)2949-2952
Number of pages4
JournalSynlett
Issue number18
DOIs
Publication statusPublished - 2009 Dec 21

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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