Self-assembly is the process where smaller components autonomously assemble to form a larger and more complex structure. One of the application areas of self-assembly is engineering and production of complicated nanostructures. Recently, researchers proposed a new folding model called the oritatami model (OM) that simulates the cotranscriptional self-assembly, based on the kinetics on the final shape of folded molecules. Nanostructures in oritatami system (OS) are represented by a sequence of beads and interactions on the lattice. We propose a method to design a general OS, which we call GEOS, that constructs a given geometric structure. The main idea is to design small modular OSs, which we call hinges, for every possible pair of adjacent points in the target structure. Once a shape filling curve for the target structure is ready, we construct an appropriate primary structure that follows the curve by a sequence of hinges. We establish generalized guidelines on designing a GEOS, and propose two GEOSs.
|Title of host publication||DNA Computing and Molecular Programming - 24th International Conference, DNA 24, 2018, Proceedings|
|Editors||David Doty, Hendrik Dietz|
|Number of pages||16|
|Publication status||Published - 2018|
|Event||24th International Conference on DNA Computing and Molecular Programming, DNA 2018 - Jinan, China|
Duration: 2018 Oct 8 → 2018 Oct 12
|Name||Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)|
|Other||24th International Conference on DNA Computing and Molecular Programming, DNA 2018|
|Period||18/10/8 → 18/10/12|
Bibliographical noteFunding Information:
This work has been supported in part by the NIH grant R01 GM109459.
This work has been supported in part by the NIH grant R01
All Science Journal Classification (ASJC) codes
- Theoretical Computer Science
- Computer Science(all)