Continuous release of bFGF from multilayer nanofilm to maintain undifferentiated human iPS cell cultures

Ju Hyun Park, Jinkee Hong

Research output: Contribution to journalArticle

9 Citations (Scopus)


In most cases, induced pluripotent stem (iPS) cells must be maintained by replacing basic fibroblast growth factor (bFGF)-containing medium daily to inhibit spontaneous differentiation. However, complete inhibition of differentiation is difficult to achieve even with frequent replacement of medium because of bFGF instability. Here, we established a novel system for the sustained release of bFGF from a modified surface by using a nanofilm fabrication method. This journal is

Original languageEnglish
Pages (from-to)1196-1200
Number of pages5
JournalIntegrative Biology (United Kingdom)
Issue number12
Publication statusPublished - 2014 Dec 1


All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry

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