Continuous release of bFGF from multilayer nanofilm to maintain undifferentiated human iPS cell cultures

Ju Hyun Park, Jinkee Hong

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In most cases, induced pluripotent stem (iPS) cells must be maintained by replacing basic fibroblast growth factor (bFGF)-containing medium daily to inhibit spontaneous differentiation. However, complete inhibition of differentiation is difficult to achieve even with frequent replacement of medium because of bFGF instability. Here, we established a novel system for the sustained release of bFGF from a modified surface by using a nanofilm fabrication method. This journal is

Original languageEnglish
Pages (from-to)1196-1200
Number of pages5
JournalIntegrative Biology (United Kingdom)
Volume6
Issue number12
DOIs
Publication statusPublished - 2014 Dec 1

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry

Fingerprint Dive into the research topics of 'Continuous release of bFGF from multilayer nanofilm to maintain undifferentiated human iPS cell cultures'. Together they form a unique fingerprint.

  • Cite this