A convergent and scalable synthetic route to a tetracyclic oligostilbenoid natural product, diptoindonesin G, is described where Suzuki-Miyaura cross-coupling and intramolecular Friedel-Crafts acylation were employed to construct the central C ring of diptoindonesin G. Two fragments for cross-coupling reaction were readily synthesized with similar efficiency.
Bibliographical noteFunding Information:
We thank the National Research Foundation of Korea ( NRF-2017R1A2A2A05069364 and NRF-2018R1A6A1A03023718 ) for generous financial support.
© 2018 Elsevier Ltd
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry