Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells

Jaemoon Yang, Jihye Choi, Doyeon Bang, Eunjung Kim, Eun Kyung Lim, Huiyul Park, Jinsuck Suh, Kwangyeol Lee, Kyung-hwa Yoo, Eunkyoung Kim, yongmin Huh, Seungjoo Haam

Research output: Contribution to journalArticle

275 Citations (Scopus)

Abstract

Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo.

Original languageEnglish
Pages (from-to)441-444
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number2
DOIs
Publication statusPublished - 2011 Jan 10

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Ablation
Cells
Nanoparticles
Infrared radiation
Infrared lasers
Laser beam effects
Polyaniline
Absorption spectra
Salts
Wavelength
Water
polyaniline

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

Yang, Jaemoon ; Choi, Jihye ; Bang, Doyeon ; Kim, Eunjung ; Lim, Eun Kyung ; Park, Huiyul ; Suh, Jinsuck ; Lee, Kwangyeol ; Yoo, Kyung-hwa ; Kim, Eunkyoung ; Huh, yongmin ; Haam, Seungjoo. / Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 2. pp. 441-444.
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Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells. / Yang, Jaemoon; Choi, Jihye; Bang, Doyeon; Kim, Eunjung; Lim, Eun Kyung; Park, Huiyul; Suh, Jinsuck; Lee, Kwangyeol; Yoo, Kyung-hwa; Kim, Eunkyoung; Huh, yongmin; Haam, Seungjoo.

In: Angewandte Chemie - International Edition, Vol. 50, No. 2, 10.01.2011, p. 441-444.

Research output: Contribution to journalArticle

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