Coronary Sinus Obstruction by Primary Cardiac Lymphoma as a Cause of Dyspnea Due to Significant Diastolic Dysfunction and Elevated Filling Pressures

Sang Min Park, ChiYoung Shim, Donghoon Choi, Ji Hyun Lee, Sung Ai Kim, Eui Young Choi, Jong Won Ha, Namsik Chung

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 52-year-old woman presented with severe dyspnea of 2 weeks' duration. Echocardiography showed an enlarged left atrium but normal global left ventricular systolic function. However, a huge, irregularly shaped mass at the dilated coronary sinus that extended into the right atrium was noted. Mitral inflow showed restrictive physiology and the E/E' ratio was significantly elevated, suggesting elevated left ventricular filling pressures. Echocardiography-guided biopsy was performed, and a diagnosis of primary cardiac lymphoma (diffuse large B-cell type) was made. After the first cycle of chemotherapy, the patient's symptom was markedly improved. A follow-up echocardiogram showed complete removal of the mass and a change in left ventricular filling pattern from restrictive to relaxation abnormality with decreased E/E'. The present case demonstrates a rare cause of diastolic dysfunction due to coronary sinus obstruction by tumor infiltration. Diastolic dysfunction caused by coronary sinus obstruction was improved after the tumor was resolved by chemotherapy.

Original languageEnglish
JournalJournal of the American Society of Echocardiography
Volume23
Issue number6
DOIs
Publication statusPublished - 2010 Jun 1

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Coronary Sinus
Dyspnea
Lymphoma
Heart Atria
Pressure
Echocardiography
Drug Therapy
Lymphoma, Large B-Cell, Diffuse
Ventricular Pressure
Left Ventricular Function
Neoplasms
Biopsy

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Coronary Sinus Obstruction by Primary Cardiac Lymphoma as a Cause of Dyspnea Due to Significant Diastolic Dysfunction and Elevated Filling Pressures",
abstract = "A 52-year-old woman presented with severe dyspnea of 2 weeks' duration. Echocardiography showed an enlarged left atrium but normal global left ventricular systolic function. However, a huge, irregularly shaped mass at the dilated coronary sinus that extended into the right atrium was noted. Mitral inflow showed restrictive physiology and the E/E' ratio was significantly elevated, suggesting elevated left ventricular filling pressures. Echocardiography-guided biopsy was performed, and a diagnosis of primary cardiac lymphoma (diffuse large B-cell type) was made. After the first cycle of chemotherapy, the patient's symptom was markedly improved. A follow-up echocardiogram showed complete removal of the mass and a change in left ventricular filling pattern from restrictive to relaxation abnormality with decreased E/E'. The present case demonstrates a rare cause of diastolic dysfunction due to coronary sinus obstruction by tumor infiltration. Diastolic dysfunction caused by coronary sinus obstruction was improved after the tumor was resolved by chemotherapy.",
author = "Park, {Sang Min} and ChiYoung Shim and Donghoon Choi and Lee, {Ji Hyun} and Kim, {Sung Ai} and Choi, {Eui Young} and Ha, {Jong Won} and Namsik Chung",
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Coronary Sinus Obstruction by Primary Cardiac Lymphoma as a Cause of Dyspnea Due to Significant Diastolic Dysfunction and Elevated Filling Pressures. / Park, Sang Min; Shim, ChiYoung; Choi, Donghoon; Lee, Ji Hyun; Kim, Sung Ai; Choi, Eui Young; Ha, Jong Won; Chung, Namsik.

In: Journal of the American Society of Echocardiography, Vol. 23, No. 6, 01.06.2010.

Research output: Contribution to journalArticle

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AU - Park, Sang Min

AU - Shim, ChiYoung

AU - Choi, Donghoon

AU - Lee, Ji Hyun

AU - Kim, Sung Ai

AU - Choi, Eui Young

AU - Ha, Jong Won

AU - Chung, Namsik

PY - 2010/6/1

Y1 - 2010/6/1

N2 - A 52-year-old woman presented with severe dyspnea of 2 weeks' duration. Echocardiography showed an enlarged left atrium but normal global left ventricular systolic function. However, a huge, irregularly shaped mass at the dilated coronary sinus that extended into the right atrium was noted. Mitral inflow showed restrictive physiology and the E/E' ratio was significantly elevated, suggesting elevated left ventricular filling pressures. Echocardiography-guided biopsy was performed, and a diagnosis of primary cardiac lymphoma (diffuse large B-cell type) was made. After the first cycle of chemotherapy, the patient's symptom was markedly improved. A follow-up echocardiogram showed complete removal of the mass and a change in left ventricular filling pattern from restrictive to relaxation abnormality with decreased E/E'. The present case demonstrates a rare cause of diastolic dysfunction due to coronary sinus obstruction by tumor infiltration. Diastolic dysfunction caused by coronary sinus obstruction was improved after the tumor was resolved by chemotherapy.

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