Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012)

Knut M. Wittkowski; Christina Dadurian; Martin P. Seybold; Han Sang Kim; Ayuko Hoshino; David Lyden

doi:10.1371/journal.pone.0214826

Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012)

Knut M. Wittkowski, Christina Dadurian, Martin P. Seybold, Han Sang Kim, Ayuko Hoshino, David Lyden

Department of Internal Medicine

Research output: Contribution to journal › Comment/debate › peer-review

1 Citation (Scopus)

Abstract

In the “HPaCD is more effective than HPbCD against migration of breast cancer cells” subsection of the Results (page 14 of the PDF file), the first word of the third paragraph is incorrect. The cyclodextrin used in [72–74] was MβCD. In this study, the authors used HP cyclodextrins because of lower cytotoxicity. Thus, the second sentence in this paragraph is incorrect. The correct sentence is: To determine whether inhibition of migration is caused by cyclodextrins depleting cholesterol, as assumed previously, the published activity from wound healing experiments comparing MβCD against control was replicated using HPβCD, and complemented with novel activity results comparing HPαCD against control, both in MDA-MB 231 (ER-) and MCF-7 (ER+) human breast epithelial cell lines.

Original language	English
Article number	e0214826
Journal	PloS one
Volume	14
Issue number	3
DOIs	https://doi.org/10.1371/journal.pone.0214826
Publication status	Published - 2019 Mar

Bibliographical note

Publisher Copyright:
© 2019 Wittkowski et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)
General

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1371/journal.pone.0214826

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title = "Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012)",

abstract = "In the “HPaCD is more effective than HPbCD against migration of breast cancer cells” subsection of the Results (page 14 of the PDF file), the first word of the third paragraph is incorrect. The cyclodextrin used in [72–74] was MβCD. In this study, the authors used HP cyclodextrins because of lower cytotoxicity. Thus, the second sentence in this paragraph is incorrect. The correct sentence is: To determine whether inhibition of migration is caused by cyclodextrins depleting cholesterol, as assumed previously, the published activity from wound healing experiments comparing MβCD against control was replicated using HPβCD, and complemented with novel activity results comparing HPαCD against control, both in MDA-MB 231 (ER-) and MCF-7 (ER+) human breast epithelial cell lines.",

author = "Wittkowski, {Knut M.} and Christina Dadurian and Seybold, {Martin P.} and Kim, {Han Sang} and Ayuko Hoshino and David Lyden",

note = "Publisher Copyright: {\textcopyright} 2019 Wittkowski et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2019",

month = mar,

doi = "10.1371/journal.pone.0214826",

language = "English",

volume = "14",

journal = "PLoS One",

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Correction : Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012). / Wittkowski, Knut M.; Dadurian, Christina; Seybold, Martin P. et al.

In: PloS one, Vol. 14, No. 3, e0214826, 03.2019.

Research output: Contribution to journal › Comment/debate › peer-review

TY - JOUR

T1 - Correction

T2 - Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012)

AU - Wittkowski, Knut M.

AU - Dadurian, Christina

AU - Seybold, Martin P.

AU - Kim, Han Sang

AU - Hoshino, Ayuko

AU - Lyden, David

N1 - Publisher Copyright: © 2019 Wittkowski et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2019/3

Y1 - 2019/3

N2 - In the “HPaCD is more effective than HPbCD against migration of breast cancer cells” subsection of the Results (page 14 of the PDF file), the first word of the third paragraph is incorrect. The cyclodextrin used in [72–74] was MβCD. In this study, the authors used HP cyclodextrins because of lower cytotoxicity. Thus, the second sentence in this paragraph is incorrect. The correct sentence is: To determine whether inhibition of migration is caused by cyclodextrins depleting cholesterol, as assumed previously, the published activity from wound healing experiments comparing MβCD against control was replicated using HPβCD, and complemented with novel activity results comparing HPαCD against control, both in MDA-MB 231 (ER-) and MCF-7 (ER+) human breast epithelial cell lines.

AB - In the “HPaCD is more effective than HPbCD against migration of breast cancer cells” subsection of the Results (page 14 of the PDF file), the first word of the third paragraph is incorrect. The cyclodextrin used in [72–74] was MβCD. In this study, the authors used HP cyclodextrins because of lower cytotoxicity. Thus, the second sentence in this paragraph is incorrect. The correct sentence is: To determine whether inhibition of migration is caused by cyclodextrins depleting cholesterol, as assumed previously, the published activity from wound healing experiments comparing MβCD against control was replicated using HPβCD, and complemented with novel activity results comparing HPαCD against control, both in MDA-MB 231 (ER-) and MCF-7 (ER+) human breast epithelial cell lines.

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Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer(PLoS ONE (2018) 13:7(e0199012) DOI: 10.1371/journal.pone.0199012)

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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