Abstract
We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.
| Original language | English |
|---|---|
| Pages (from-to) | 1975-1977 |
| Number of pages | 3 |
| Journal | Movement Disorders |
| Volume | 21 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2006 Nov 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Clinical Neurology
- Neuroscience(all)
Cite this
}
Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy. / Lee, philhyu; Yeo, Seung Hyeon; Kim, Hyun Joon; Youm, Hyo Young.
In: Movement Disorders, Vol. 21, No. 11, 01.11.2006, p. 1975-1977.Research output: Contribution to journal › Article
TY - JOUR
T1 - Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
AU - Lee, philhyu
AU - Yeo, Seung Hyeon
AU - Kim, Hyun Joon
AU - Youm, Hyo Young
PY - 2006/11/1
Y1 - 2006/11/1
N2 - We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.
AB - We investigated an association between olfaction and cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross-Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD.
UR - http://www.scopus.com/inward/record.url?scp=33845186324&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845186324&partnerID=8YFLogxK
U2 - 10.1002/mds.21083
DO - 10.1002/mds.21083
M3 - Article
C2 - 16960860
AN - SCOPUS:33845186324
VL - 21
SP - 1975
EP - 1977
JO - Movement Disorders
JF - Movement Disorders
SN - 0885-3185
IS - 11
ER -