Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention

Jung Sun Kim, Young Guk Ko, Se Jung Yoon, Jae Youn Moon, Jin Kim Young, Wook Choi Byoung, Donghoon Choi, Yangsoo Jang

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.

Original languageEnglish
Pages (from-to)1621-1626
Number of pages6
JournalCirculation Journal
Volume72
Issue number10
DOIs
Publication statusPublished - 2008 Oct 3

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Percutaneous Coronary Intervention
Magnetic Resonance Imaging
Ventricular Remodeling
Left Ventricular Dysfunction
Stroke Volume
Pain

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

@article{2962e86e59ee4b6ea85ff9e47ba0e61a,
title = "Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention",
abstract = "Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70{\%} STR (group 1, n=21) and <70{\%} STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1{\%} vs 91.7{\%}, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7{\%} vs 29.1± 13.4{\%}, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9{\%} vs 47.8±11.1{\%}, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.",
author = "Kim, {Jung Sun} and Ko, {Young Guk} and Yoon, {Se Jung} and Moon, {Jae Youn} and Young, {Jin Kim} and Byoung, {Wook Choi} and Donghoon Choi and Yangsoo Jang",
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language = "English",
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Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention. / Kim, Jung Sun; Ko, Young Guk; Yoon, Se Jung; Moon, Jae Youn; Young, Jin Kim; Byoung, Wook Choi; Choi, Donghoon; Jang, Yangsoo.

In: Circulation Journal, Vol. 72, No. 10, 03.10.2008, p. 1621-1626.

Research output: Contribution to journalArticle

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T1 - Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention

AU - Kim, Jung Sun

AU - Ko, Young Guk

AU - Yoon, Se Jung

AU - Moon, Jae Youn

AU - Young, Jin Kim

AU - Byoung, Wook Choi

AU - Choi, Donghoon

AU - Jang, Yangsoo

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N2 - Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.

AB - Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.

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