Abstract
Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.
| Original language | English |
|---|---|
| Pages (from-to) | 1621-1626 |
| Number of pages | 6 |
| Journal | Circulation Journal |
| Volume | 72 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2008 Oct 3 |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
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Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention. / Kim, Jung Sun; Ko, Young Guk; Yoon, Se Jung; Moon, Jae Youn; Young, Jin Kim; Byoung, Wook Choi; Choi, Donghoon; Jang, Yangsoo.
In: Circulation Journal, Vol. 72, No. 10, 03.10.2008, p. 1621-1626.Research output: Contribution to journal › Article
TY - JOUR
T1 - Correlation of serial cardiac magnetic resonance imaging parameters with early resolution of ST-segment elevation after primary percutaneous coronary intervention
AU - Kim, Jung Sun
AU - Ko, Young Guk
AU - Yoon, Se Jung
AU - Moon, Jae Youn
AU - Young, Jin Kim
AU - Byoung, Wook Choi
AU - Choi, Donghoon
AU - Jang, Yangsoo
PY - 2008/10/3
Y1 - 2008/10/3
N2 - Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.
AB - Background: The aim of the present study was to determine whether the parameters of cardiac magnetic resonance imaging (CMRI) might correlate with early ST-segment resolution (STR) after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). Methods and Results: CMRI was performed in 45 STEMI patients (age: 56.6±13.0 years) at 8.2±8.0 days (early phase) and 3.3±1.1 months (late phase) after successful PCI. CMRI parameters were compared between 2 groups: ≥70% STR (group 1, n=21) and <70% STR (group 2, n=24). Both groups had similar baseline characteristics, except for a higher frequency of ≥2 myocardial blush grade and shorter pain-to-balloon time in group 1. Early-phase CMRI showed that persistent microvascular obstruction (PMO) (38.1% vs 91.7%, p<0.001) occurred less frequently and the percent infarct mass against total left ventricular (LV) mass (17.7±8.7% vs 29.1± 13.4%, p=0.001) was smaller in group 1. Late-phase CMRI revealed a significant increase in LV end-diastolic volume (-1.5±8.7 vs 14.5±25.5 ml, p=0.026) and reduced ejection fraction (55.0±9.9% vs 47.8±11.1%, p=0.027) in group 2. Conclusions: CMRI demonstrated that early STR might be related to PMO and infarct size, and predicts LV dysfunction and adverse LV remodeling. Also, early-phase CMRI findings are comparable to late-phase CMRI in association with early STR.
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U2 - 10.1253/circj.CJ-08-0232
DO - 10.1253/circj.CJ-08-0232
M3 - Article
C2 - 18756038
AN - SCOPUS:52749087835
VL - 72
SP - 1621
EP - 1626
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 10
ER -