CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Wonmok Lee, Hae Sun Chung, Hyukmin Lee, Jong Hwa Yum, DongEun Yong, Seokhoon Jeong, Kyungwon Lee, Yunsop Chong

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalAnnals of Laboratory Medicine
Volume33
Issue number2
DOIs
Publication statusPublished - 2013 Apr 17

Fingerprint

Shigella sonnei
China
Genes
Cefotaxime
Insertional Mutagenesis
Pulsed Field Gel Electrophoresis
Pathogens
Southern Blotting
Electrophoresis
Escherichia coli
Abdominal Pain
Diarrhea
Plasmids
Fever
Gels
Infection

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

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abstract = "We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.",
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CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China. / Lee, Wonmok; Chung, Hae Sun; Lee, Hyukmin; Yum, Jong Hwa; Yong, DongEun; Jeong, Seokhoon; Lee, Kyungwon; Chong, Yunsop.

In: Annals of Laboratory Medicine, Vol. 33, No. 2, 17.04.2013, p. 141-144.

Research output: Contribution to journalArticle

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