Current status of human papillomavirus infection and introduction of vaccination to the national immunization program in Korea

An overview

Min A. Kim, Gwan Hee Han, Jae-Hoon Kim, Kyung Seo

Research output: Contribution to journalReview article

Abstract

Human Papillomavirus (HPV) infection is the most common sexually transmitted infection and is associated with the development of cervical cancer. The purpose of this report is to provide the literature evidences on selecting the HPV vaccine for national immunization program (NIP) in Korea. To complete these tasks, we reviewed domestic and foreign literature on the current status of HPV infection, efficacy and effectiveness of HPV vaccine, safety of vaccine and cost effectiveness analysis of vaccination business. Given that the median age of first sexual intercourse is continuing to fall, this may have serious implications for HPV infection and cervical cancer incidence at the age of 20s. The World Health Organization recommends that the HPV vaccination should be included in the NIP being implemented in each country. Both the bivalent and quadrivalent vaccines have a 90% or greater preventive efficacy on cervical intraepithelial lesion 2-3 and cervical cancer by the HPV 16 or HPV 18. In the future, if HPV vaccination rate as part of NIP increases, it is expected that the incidence of HPV infection, genital warts, and cervical precancerous lesions will be decreased in the vaccination age group. Therefore, in order to increase the HPV vaccination rate at this point in Korea, social consensus and efforts such as the introduction and promotion of HPV vaccine to the NIP according to appropriate cost-effectiveness analysis are required.

Original languageEnglish
Article numbere331
JournalJournal of Korean medical science
Volume33
Issue number52
DOIs
Publication statusPublished - 2018 Dec 24

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Immunization Programs
Papillomavirus Infections
Korea
Vaccination
Papillomavirus Vaccines
Uterine Cervical Neoplasms
Coitus
Cost-Benefit Analysis
Vaccines
Human papillomavirus 18
Condylomata Acuminata
Human papillomavirus 16
Incidence
Sexually Transmitted Diseases
Consensus
Age Groups
Safety

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Human Papillomavirus (HPV) infection is the most common sexually transmitted infection and is associated with the development of cervical cancer. The purpose of this report is to provide the literature evidences on selecting the HPV vaccine for national immunization program (NIP) in Korea. To complete these tasks, we reviewed domestic and foreign literature on the current status of HPV infection, efficacy and effectiveness of HPV vaccine, safety of vaccine and cost effectiveness analysis of vaccination business. Given that the median age of first sexual intercourse is continuing to fall, this may have serious implications for HPV infection and cervical cancer incidence at the age of 20s. The World Health Organization recommends that the HPV vaccination should be included in the NIP being implemented in each country. Both the bivalent and quadrivalent vaccines have a 90{\%} or greater preventive efficacy on cervical intraepithelial lesion 2-3 and cervical cancer by the HPV 16 or HPV 18. In the future, if HPV vaccination rate as part of NIP increases, it is expected that the incidence of HPV infection, genital warts, and cervical precancerous lesions will be decreased in the vaccination age group. Therefore, in order to increase the HPV vaccination rate at this point in Korea, social consensus and efforts such as the introduction and promotion of HPV vaccine to the NIP according to appropriate cost-effectiveness analysis are required.",
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Current status of human papillomavirus infection and introduction of vaccination to the national immunization program in Korea : An overview. / Kim, Min A.; Han, Gwan Hee; Kim, Jae-Hoon; Seo, Kyung.

In: Journal of Korean medical science, Vol. 33, No. 52, e331, 24.12.2018.

Research output: Contribution to journalReview article

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