Current status of radical prostatectomy for high-risk prostate cancer

Ho Won Kang, Joo Yong Lee, Jong Kyou Kwon, Seong Uk Jeh, Hae Do Jung, Young Deuk Choi

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Despite the wide application of prostate-specific antigen-based screening leading to a profound stage migration in prostate cancer (PC), a significant percentage of men are still being diagnosed with clinically high-risk disease that requires aggressive treatment. Optimal management in these patients remains challenging, and strong advocates for radical prostatectomy (RP), radiotherapy, androgen deprivation therapy, and, increasingly, a multimodal approach abound. Currently, surgery for high-risk PC is frequently applied. RP offers an attractive opportunity for tumor excision either as a definitive management or as a first step in multimodal therapy. Nevertheless, this approach is still controversial. In this review, we discuss the current evidence for the role of RP in this clinical setting, including surgical considerations and outcomes. The role of robot-assisted RP, which is increasingly utilized in Korea in this clinical scenario, is discussed.

Original languageEnglish
Pages (from-to)629-635
Number of pages7
JournalKorean Journal of Urology
Volume55
Issue number10
DOIs
Publication statusPublished - 2014 Oct 1

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Prostatectomy
Prostatic Neoplasms
Prostate-Specific Antigen
Korea
Androgens
Radiotherapy
Therapeutics
Neoplasms

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Kang, Ho Won ; Lee, Joo Yong ; Kwon, Jong Kyou ; Jeh, Seong Uk ; Jung, Hae Do ; Choi, Young Deuk. / Current status of radical prostatectomy for high-risk prostate cancer. In: Korean Journal of Urology. 2014 ; Vol. 55, No. 10. pp. 629-635.
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Current status of radical prostatectomy for high-risk prostate cancer. / Kang, Ho Won; Lee, Joo Yong; Kwon, Jong Kyou; Jeh, Seong Uk; Jung, Hae Do; Choi, Young Deuk.

In: Korean Journal of Urology, Vol. 55, No. 10, 01.10.2014, p. 629-635.

Research output: Contribution to journalReview article

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