Cutaneous metastasis of choriocarcinoma

A case report

Gun Park Sang, Yong Chang Jae, SeHoon Kim, Dongsik Bang

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Choriocarcinoma is one of the malignant tumors of trophoblastic cells characterized by the secretion of human chorionic gonadotrophin (hCG) (1-3). Cutaneous metastasis is a rare presentation of Choriocarcinoma but a poor prognostic sign because it is associated only with widespread disease (3-5). A 52-yr-old female complaining of dyspnea for 2 months, presented with fingertip sized erythematous nodules on the left side of the neck and the right side of the upper back of 1 month duraton. She has suffered from Behçet's disease since 1999. Microscopic examination of a nodule of upper back demonstrated biphasic pattern of cytotrophoblasts and hCG-positive syncytiotrophoblasts, and the typical histologic features of choriocarcinoma. She was referred to the gynecological oncology department. After 17 cycles of combination chemotherapy, the serum hCG level has fallen from 700,000 to under 2.0 mlU/mL and the skin lesions have almost disappeared. However, after 3 months, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed due to elevated serum hCG level (4,447.7 mIU/mL), and she is scheduled to receive post-operative adjuvant chemotherapy.

Original languageEnglish
Pages (from-to)683-686
Number of pages4
JournalJournal of Korean Medical Science
Volume20
Issue number4
Publication statusPublished - 2005 Aug 1

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Choriocarcinoma
Chorionic Gonadotropin
Neoplasm Metastasis
Skin
Trophoblasts
Trophoblastic Neoplasms
Ovariectomy
Adjuvant Chemotherapy
Combination Drug Therapy
Serum
Hysterectomy
Dyspnea
Neck

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Sang, G. P., Jae, Y. C., Kim, S., & Bang, D. (2005). Cutaneous metastasis of choriocarcinoma: A case report. Journal of Korean Medical Science, 20(4), 683-686.
Sang, Gun Park ; Jae, Yong Chang ; Kim, SeHoon ; Bang, Dongsik. / Cutaneous metastasis of choriocarcinoma : A case report. In: Journal of Korean Medical Science. 2005 ; Vol. 20, No. 4. pp. 683-686.
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Sang, GP, Jae, YC, Kim, S & Bang, D 2005, 'Cutaneous metastasis of choriocarcinoma: A case report', Journal of Korean Medical Science, vol. 20, no. 4, pp. 683-686.

Cutaneous metastasis of choriocarcinoma : A case report. / Sang, Gun Park; Jae, Yong Chang; Kim, SeHoon; Bang, Dongsik.

In: Journal of Korean Medical Science, Vol. 20, No. 4, 01.08.2005, p. 683-686.

Research output: Contribution to journalArticle

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