Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application

Dong Hyun Kim; Se Ho Lee; Kyoung Nam Kim; Kwang Mahn Kim; In Bo Shim; Yong Keun Lee

doi:10.1016/j.jmmm.2005.02.078

Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application

Dong Hyun Kim, Se Ho Lee, Kyoung Nam Kim, Kwang Mahn Kim, In Bo Shim, Yong Keun Lee

Department of Dental Biomaterials and Bioengineering

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe₃O₄ and SrFe₁₂O₁₉ ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic.

Original language	English
Pages (from-to)	287-292
Number of pages	6
Journal	Journal of Magnetism and Magnetic Materials
Volume	293
Issue number	1
DOIs	https://doi.org/10.1016/j.jmmm.2005.02.078
Publication status	Published - 2005 May

Bibliographical note

Funding Information:
This work was supported by Grant No. R01-2001-000-00157 from the Basic Research Program of the Korea Science & Engineering Foundation.

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics

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title = "Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application",

abstract = "We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe3O4 and SrFe12O19 ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic.",

author = "Kim, {Dong Hyun} and Lee, {Se Ho} and Kim, {Kyoung Nam} and Kim, {Kwang Mahn} and Shim, {In Bo} and Lee, {Yong Keun}",

note = "Funding Information: This work was supported by Grant No. R01-2001-000-00157 from the Basic Research Program of the Korea Science & Engineering Foundation. ",

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AU - Kim, Dong Hyun

AU - Lee, Se Ho

AU - Kim, Kyoung Nam

AU - Kim, Kwang Mahn

AU - Shim, In Bo

AU - Lee, Yong Keun

N1 - Funding Information: This work was supported by Grant No. R01-2001-000-00157 from the Basic Research Program of the Korea Science & Engineering Foundation.

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AB - We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe3O4 and SrFe12O19 ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic.

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