Cytotoxicity of Group 5 Transition Metal Ditellurides (MTe2; M=V, Nb, Ta)

Hui Ling Chia, Naziah Mohamad Latiff, Zdenĕk Sofer, Martin Pumera

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


Much research effort has been put in to study layered compounds with transition metal dichalcogenides (TMDs) being one of the most studied compounds. Due to their extraordinary properties such as excellent electrochemical properties, tuneable band gaps, and low shear resistance due to weak van der Waals interactions between layers, TMDs have been found to have wide applications such as electrocatalysts for hydrogen evolution reactions, supercapacitors, biosensors, field-effect transistors (FETs), photovoltaics, and lubricant additives. In very recent years, Group 5 transition metal ditellurides have received an immense amount of research attention. However to date, little has been known of the potential toxicities posed by these materials. As such, we conducted the cytotoxicity study by incubating various concentrations of the Group 5 transition metal ditellurides (MTe2; M=V, Nb, Ta) with human lung carcinoma epithelial A549 cells for 24 hours and the remaining cell viabilities after treatment was measured. Our findings indicate that VTe2 is highly toxic whereas NbTe2 and TaTe2 are deemed to exhibit mild toxicities. This study constitutes an exemplary first step towards the understanding of the Group 5 transition metal ditellurides’ toxicity effects in preparation for their possible future commercialisation.

Original languageEnglish
Pages (from-to)206-211
Number of pages6
JournalChemistry - A European Journal
Issue number1
Publication statusPublished - 2018 Jan 2

Bibliographical note

Funding Information:
Z.S. was supported by Czech Science Foundation (GACR No. 17-11456S). This work was created with the financial support of the Neuron Foundation for science support. M.P. thanks Tier 1 (99/13) from Ministry of Education for funding.

Publisher Copyright:
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry


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