Daily exceedance concentration hours: A novel indicator to measure acute cardiovascular effects of PM2.5 in six Chinese subtropical cities

Hualiang Lin; Xiaojie Wang; Zhengmin (Min) Qian; Shu Guo; Zhenjiang Yao; Michael G. Vaughn; Guanghui Dong; Tao Liu; Jianpeng Xiao; Xing Li; Weilin Zeng; Yanjun Xu; Wenjun Ma

doi:10.1016/j.envint.2017.11.022

Daily exceedance concentration hours: A novel indicator to measure acute cardiovascular effects of PM_2.5 in six Chinese subtropical cities

Hualiang Lin, Xiaojie Wang, Zhengmin (Min) Qian, Shu Guo, Zhenjiang Yao, Michael G. Vaughn, Guanghui Dong, Tao Liu, Jianpeng Xiao, Xing Li, Weilin Zeng, Yanjun Xu, Wenjun Ma

Graduate School of Social Welfare

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Background Daily mean concentration cannot fully address the hourly variations of air pollution within one day. As such, we proposed a new indicator, daily exceedance concentration hours (DECH), to explore the acute cardiovascular effects of ambient PM_2.5 (particles with aerodynamic diameters less than 2.5 μm). The DECH in PM_2.5 was defined as daily total concentration-hours > 25 μg/m³. Methods A generalized additive model with a quasi-Poisson link was applied to estimate the associations between day-to-day variation in PM_2.5 DECH and day-to-day variation in cardiovascular mortality in six subtropical cities in Guangdong Province, China. Results The analysis revealed significant associations between PM_2.5 DECHs and cardiovascular mortality. A 500 μg/m³ ∗ h increase in PM_2.5 DECHs at lag₀₃ was associated with an increase of 4.55% (95% confidence interval (CI): 3.59%, 5.52%) in cardiovascular mortality, 4.45% (95% CI: 2.81%, 6.12%) in ischemic cardiovascular mortality, 5.02% (95% CI: 3.41%, 6.65%) in cerebrovascular mortality, and 3.00% (95% CI: 1.13%, 4.90%) in acute myocardial infarction mortality. We further observed a greater mortality burden using PM_2.5 DECHs than daily mean PM_2.5 (6478 (95% CI: 5071, 7917) VS 5136 (95% CI: 3990, 6305)). Conclusion This study reveals that PM_2.5 DECH is one important exposure indicator of ambient PM_2.5 to measure its cardiovascular mortality effects in Pearl River Delta region; and that using daily mean concentration could under-estimate the mortality burden compared with this new indicator.

Original language	English
Pages (from-to)	117-123
Number of pages	7
Journal	Environment International
Volume	111
DOIs	https://doi.org/10.1016/j.envint.2017.11.022
Publication status	Published - 2018 Feb

Bibliographical note

Funding Information:
This study is funded in part by supported by the Medical Science and Technology Research Foundation of Guangdong Province ( A2017269 and A2016250 ) and Key Special Project of National Key Research and Development Plan Program ( 2016YFC0207000 ).

Publisher Copyright:
© 2017

All Science Journal Classification (ASJC) codes

Environmental Science(all)

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

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Lin, Hualiang ; Wang, Xiaojie ; Qian, Zhengmin (Min) ; Guo, Shu ; Yao, Zhenjiang ; Vaughn, Michael G. ; Dong, Guanghui ; Liu, Tao ; Xiao, Jianpeng ; Li, Xing ; Zeng, Weilin ; Xu, Yanjun ; Ma, Wenjun. / Daily exceedance concentration hours : A novel indicator to measure acute cardiovascular effects of PM_2.5 in six Chinese subtropical cities. In: Environment International. 2018 ; Vol. 111. pp. 117-123.

@article{cabcaf6be2d04352b9c17f2ebb3f05d6,

title = "Daily exceedance concentration hours: A novel indicator to measure acute cardiovascular effects of PM2.5 in six Chinese subtropical cities",

abstract = "Background Daily mean concentration cannot fully address the hourly variations of air pollution within one day. As such, we proposed a new indicator, daily exceedance concentration hours (DECH), to explore the acute cardiovascular effects of ambient PM2.5 (particles with aerodynamic diameters less than 2.5 μm). The DECH in PM2.5 was defined as daily total concentration-hours > 25 μg/m3. Methods A generalized additive model with a quasi-Poisson link was applied to estimate the associations between day-to-day variation in PM2.5 DECH and day-to-day variation in cardiovascular mortality in six subtropical cities in Guangdong Province, China. Results The analysis revealed significant associations between PM2.5 DECHs and cardiovascular mortality. A 500 μg/m3 ∗ h increase in PM2.5 DECHs at lag03 was associated with an increase of 4.55% (95% confidence interval (CI): 3.59%, 5.52%) in cardiovascular mortality, 4.45% (95% CI: 2.81%, 6.12%) in ischemic cardiovascular mortality, 5.02% (95% CI: 3.41%, 6.65%) in cerebrovascular mortality, and 3.00% (95% CI: 1.13%, 4.90%) in acute myocardial infarction mortality. We further observed a greater mortality burden using PM2.5 DECHs than daily mean PM2.5 (6478 (95% CI: 5071, 7917) VS 5136 (95% CI: 3990, 6305)). Conclusion This study reveals that PM2.5 DECH is one important exposure indicator of ambient PM2.5 to measure its cardiovascular mortality effects in Pearl River Delta region; and that using daily mean concentration could under-estimate the mortality burden compared with this new indicator.",

author = "Hualiang Lin and Xiaojie Wang and Qian, {Zhengmin (Min)} and Shu Guo and Zhenjiang Yao and Vaughn, {Michael G.} and Guanghui Dong and Tao Liu and Jianpeng Xiao and Xing Li and Weilin Zeng and Yanjun Xu and Wenjun Ma",

note = "Funding Information: This study is funded in part by supported by the Medical Science and Technology Research Foundation of Guangdong Province ( A2017269 and A2016250 ) and Key Special Project of National Key Research and Development Plan Program ( 2016YFC0207000 ). Publisher Copyright: {\textcopyright} 2017",

year = "2018",

month = feb,

doi = "10.1016/j.envint.2017.11.022",

language = "English",

volume = "111",

pages = "117--123",

journal = "Environmental International",

issn = "0160-4120",

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Daily exceedance concentration hours : A novel indicator to measure acute cardiovascular effects of PM_2.5 in six Chinese subtropical cities. / Lin, Hualiang; Wang, Xiaojie; Qian, Zhengmin (Min); Guo, Shu; Yao, Zhenjiang; Vaughn, Michael G.; Dong, Guanghui; Liu, Tao; Xiao, Jianpeng; Li, Xing; Zeng, Weilin; Xu, Yanjun; Ma, Wenjun.

In: Environment International, Vol. 111, 02.2018, p. 117-123.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Daily exceedance concentration hours

T2 - A novel indicator to measure acute cardiovascular effects of PM2.5 in six Chinese subtropical cities

AU - Lin, Hualiang

AU - Wang, Xiaojie

AU - Qian, Zhengmin (Min)

AU - Guo, Shu

AU - Yao, Zhenjiang

AU - Vaughn, Michael G.

AU - Dong, Guanghui

AU - Liu, Tao

AU - Xiao, Jianpeng

AU - Li, Xing

AU - Zeng, Weilin

AU - Xu, Yanjun

AU - Ma, Wenjun

N1 - Funding Information: This study is funded in part by supported by the Medical Science and Technology Research Foundation of Guangdong Province ( A2017269 and A2016250 ) and Key Special Project of National Key Research and Development Plan Program ( 2016YFC0207000 ). Publisher Copyright: © 2017

PY - 2018/2

Y1 - 2018/2

N2 - Background Daily mean concentration cannot fully address the hourly variations of air pollution within one day. As such, we proposed a new indicator, daily exceedance concentration hours (DECH), to explore the acute cardiovascular effects of ambient PM2.5 (particles with aerodynamic diameters less than 2.5 μm). The DECH in PM2.5 was defined as daily total concentration-hours > 25 μg/m3. Methods A generalized additive model with a quasi-Poisson link was applied to estimate the associations between day-to-day variation in PM2.5 DECH and day-to-day variation in cardiovascular mortality in six subtropical cities in Guangdong Province, China. Results The analysis revealed significant associations between PM2.5 DECHs and cardiovascular mortality. A 500 μg/m3 ∗ h increase in PM2.5 DECHs at lag03 was associated with an increase of 4.55% (95% confidence interval (CI): 3.59%, 5.52%) in cardiovascular mortality, 4.45% (95% CI: 2.81%, 6.12%) in ischemic cardiovascular mortality, 5.02% (95% CI: 3.41%, 6.65%) in cerebrovascular mortality, and 3.00% (95% CI: 1.13%, 4.90%) in acute myocardial infarction mortality. We further observed a greater mortality burden using PM2.5 DECHs than daily mean PM2.5 (6478 (95% CI: 5071, 7917) VS 5136 (95% CI: 3990, 6305)). Conclusion This study reveals that PM2.5 DECH is one important exposure indicator of ambient PM2.5 to measure its cardiovascular mortality effects in Pearl River Delta region; and that using daily mean concentration could under-estimate the mortality burden compared with this new indicator.

AB - Background Daily mean concentration cannot fully address the hourly variations of air pollution within one day. As such, we proposed a new indicator, daily exceedance concentration hours (DECH), to explore the acute cardiovascular effects of ambient PM2.5 (particles with aerodynamic diameters less than 2.5 μm). The DECH in PM2.5 was defined as daily total concentration-hours > 25 μg/m3. Methods A generalized additive model with a quasi-Poisson link was applied to estimate the associations between day-to-day variation in PM2.5 DECH and day-to-day variation in cardiovascular mortality in six subtropical cities in Guangdong Province, China. Results The analysis revealed significant associations between PM2.5 DECHs and cardiovascular mortality. A 500 μg/m3 ∗ h increase in PM2.5 DECHs at lag03 was associated with an increase of 4.55% (95% confidence interval (CI): 3.59%, 5.52%) in cardiovascular mortality, 4.45% (95% CI: 2.81%, 6.12%) in ischemic cardiovascular mortality, 5.02% (95% CI: 3.41%, 6.65%) in cerebrovascular mortality, and 3.00% (95% CI: 1.13%, 4.90%) in acute myocardial infarction mortality. We further observed a greater mortality burden using PM2.5 DECHs than daily mean PM2.5 (6478 (95% CI: 5071, 7917) VS 5136 (95% CI: 3990, 6305)). Conclusion This study reveals that PM2.5 DECH is one important exposure indicator of ambient PM2.5 to measure its cardiovascular mortality effects in Pearl River Delta region; and that using daily mean concentration could under-estimate the mortality burden compared with this new indicator.

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