Decreased macrophage density on carbon nanofiber patterns

Jong Youl Kim, Dongwoo Khang, Jong Eun Lee, Thomas J. Webster

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, increased functions of an inflammatory cell (specifically, macrophages) specifically on aligned polycarbonate urethane (PCU) regions rather than on carbon nanofiber (CNFs) regions are described. Specifically, the results showed for the first time that macrophage adhesion and proliferation on aligned CNFs were significantly less than on PCU. The present in vitro study thus provided evidence of the ability of CNFs to down-regulate macrophage adhesion and proliferation important to decrease harmful inflammatory responses, criteria imperative for the future consideration of CNFs for numerous implant applications.

Original languageEnglish
Title of host publicationMaterials Research Society Symposium Proceedings
PublisherMaterials Research Society
Pages155-161
Number of pages7
ISBN (Print)9781604234060
DOIs
Publication statusPublished - 2006
Event2006 MRS Fall Meeting - Boston, MA, United States
Duration: 2006 Nov 272006 Dec 1

Publication series

NameMaterials Research Society Symposium Proceedings
Volume950
ISSN (Print)0272-9172

Other

Other2006 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period06/11/2706/12/1

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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    Kim, J. Y., Khang, D., Lee, J. E., & Webster, T. J. (2006). Decreased macrophage density on carbon nanofiber patterns. In Materials Research Society Symposium Proceedings (pp. 155-161). (Materials Research Society Symposium Proceedings; Vol. 950). Materials Research Society. https://doi.org/10.1557/proc-0950-d04-23