Deep Learning for Automatic Detection of Periodic Limb Movement Disorder Based on Electrocardiogram Signals

Erdenebayar Urtnasan, Jong Uk Park, Jung Hun Lee, Sang Baek Koh, Kyoung Joung Lee

Research output: Contribution to journalArticlepeer-review


In this study, a deep learning model (deepPLM) is shown to automatically detect periodic limb movement syndrome (PLMS) based on electrocardiogram (ECG) signals. The designed deepPLM model consists of four 1D convolutional layers, two long short-term memory units, and a fully connected layer. The Osteoporotic Fractures in Men sleep (MrOS) study dataset was used to construct the model, including training, validating, and testing the model. A single-lead ECG signal of the polysomnographic recording was used for each of the 52 subjects (26 controls and 26 patients) in the MrOS dataset. The ECG signal was normalized and segmented (10 s duration), and it was divided into a training set (66,560 episodes), a validation set (16,640 episodes), and a test set (20,800 episodes). The performance evaluation of the deepPLM model resulted in an F1-score of 92.0%, a precision score of 90.0%, and a recall score of 93.0% for the control set, and 92.0%, 93.0%, and 90.0%, respectively, for the patient set. The results demonstrate the possibility of automatic PLMS detection in patients by using the deepPLM model based on a single-lead ECG. This could be an alternative method for PLMS screening and a helpful tool for home healthcare services for the elderly population.

Original languageEnglish
Article number2149
Issue number9
Publication statusPublished - 2022 Sept

Bibliographical note

Funding Information:
This research was supported by the National Information Society Agency (NIA) and funded by the Ministry of Science and ICT through the Big Data Platform and Center Construction Project (No. 2022-Data-W18). This research was partially supported by a grant of the Medical data-driven hospital support project through the Korea Health Information Service (KHIS), funded by the Ministry of Health and Welfare, Republic of Korea. This research was partially supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea (NRF-2020S1A5A2A03045088).

Publisher Copyright:
© 2022 by the authors.

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry


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