Deficiencies in proteins C and S in a patient with idiopathic portal hypertension accompanied by portal vein thrombosis

Sena Hwang, Do Young Kim, Minju Kim, Young Eun Chon, Hyun Jung Lee, Young Nyun Park, Jun Yong Park, Sang Hoon Ahn, Kwang Hyub Han, Chae Yoon Chon

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have a close relation with PVT. PVT is known to have several predisposing conditions, including infection, malignancies, and coagulation disorders. There is growing interest and recognition that deficiencies in proteins C and S are associated with a hypercoagulable state. These deficiencies are regarded as key factors of systemic hypercoagulability and recurrent venous thromboembolism. We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S.

Original languageEnglish
Pages (from-to)176-181
Number of pages6
JournalThe Korean journal of hepatology
Volume16
Issue number2
DOIs
Publication statusPublished - 2010 Jun

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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