Definitions and outcome measures for mucous membrane pemphigoid: Recommendations of an international panel of experts

Dedee F. Murrell, Branka Marinovic, Frederic Caux, Catherine Prost, Razzaque Ahmed, Katarzyna Wozniak, Masayuki Amagai, Johann Bauer, Stefan Beissert, Luca Borradori, Donna Culton, Janet A. Fairley, David Fivenson, Marcel F. Jonkman, M. Peter Marinkovich, David Woodley, John Zone, Valeria Aoki, Philippe Bernard, Leen Bruckner-TudermanGiuseppe Cianchini, Vanessa Venning, Luis Diaz, Rudiger Eming, Sergei A. Grando, Russell P. Hall, Takashi Hashimoto, Josep E. Herrero-González, Michael Hertl, Pascal Joly, Sarolta Karpati, Jaehwan Kim, Soo Chan Kim, Neil J. Korman, Cezary Kowalewski, Sang Eun Lee, David R. Rubenstein, Eli Sprecher, Kim Yancey, Giovann Zambruno, Detlef Zillikens, Serge Doan, Benjamin S. Daniel, Victoria P. Werth

Research output: Contribution to journalReview articlepeer-review

85 Citations (Scopus)

Abstract

Mucous membrane pemphigoid encompasses a group of autoimmune bullous diseases with a similar phenotype characterized by subepithelial blisters, erosions, and scarring of mucous membranes, skin, or both. Although knowledge about autoimmune bullous disease is increasing, there is often a lack of clear definitions of disease, outcome measures, and therapeutic end points. With clearer definitions and outcome measures, it is possible to directly compare the results and data from various studies using meta-analyses. This consensus statement provides accurate and reproducible definitions for disease extent, activity, outcome measures, end points, and therapeutic response for mucous membrane pemphigoid and proposes a disease extent score, the Mucous Membrane Pemphigoid Disease Area Index.

Original languageEnglish
Pages (from-to)168-174
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume72
Issue number1
DOIs
Publication statusPublished - 2015 Jan 1

Bibliographical note

Funding Information:
The International Pemphigus and Pemphigoid Foundation generously supported hiring rooms at the Annual Meetings of the American Academy of Dermatology and European Academy of Dermatology and Venereology as well as audiovisual equipment and open access. The Korean World Congress Committee and the Society for Investigative Dermatology provided meeting rooms. This material is based on work supported by the Department of Veterans Affairs (Veterans Health Administration, Office of Research and Development, Biomedical Laboratory Research and Development) and by the National Institutes of Health ( NIH K24-AR 02207 ) to Dr Werth.

Publisher Copyright:
© 2014 American Academy of Dermatology, Inc.

All Science Journal Classification (ASJC) codes

  • Dermatology

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