Deformylative Intramolecular Hydroarylation: Synthesis of Benzo[e]pyrido[1,2-a]indoles

Youngeun Jung, Ikyon Kim

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Attempted cyclization of indolizines bearing both formyl and alkyne groups under acid catalysis provided benzo[e]pyrido[1,2-a]indoles with an aryl substituent at the C6 position as major products, along with the expected C5-acylated benzo[e]pyrido[1,2-a]indoles as minor ones, which resulted from preferential deformylative intramolecular hydroarylation instead of intended alkyne-carbonyl metathesis.

Original languageEnglish
Pages (from-to)4600-4603
Number of pages4
JournalOrganic Letters
Volume17
Issue number18
DOIs
Publication statusPublished - 2015 Sep 18

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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