Abstract
Attempted cyclization of indolizines bearing both formyl and alkyne groups under acid catalysis provided benzo[e]pyrido[1,2-a]indoles with an aryl substituent at the C6 position as major products, along with the expected C5-acylated benzo[e]pyrido[1,2-a]indoles as minor ones, which resulted from preferential deformylative intramolecular hydroarylation instead of intended alkyne-carbonyl metathesis.
| Original language | English |
|---|---|
| Pages (from-to) | 4600-4603 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 17 |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - 2015 Sep 18 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Cite this
Jung, Y., & Kim, I. (2015). Deformylative Intramolecular Hydroarylation: Synthesis of Benzo[e]pyrido[1,2-a]indoles. Organic Letters, 17(18), 4600-4603. https://doi.org/10.1021/acs.orglett.5b02331