Delayed enhancement in hypertrophic cardiomyopathy: Comparison with myocardial tagging MRI

Jin Kim Young, Wook Choi Byoung, Jin Hur, Hye Jeong Lee, Seung Seo Jae, Hoon Kim Tae, Ok Choe Kyu, Jong Won Ha

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Purpose: To evaluate the relationship between delayed enhancement (DE) and regional left ventricular function in hypertrophic cardiomyopathy (HCM) using gadolinium enhancement MRI and myocardial tagging MRI. Materials and Methods: Cine imaging, delayed enhancement Imaging, and tagging MRI were performed in 25 patients with HCM. The location, pattern, and extent of DE were evaluated. Circumferential shortening (Ecc) was obtained by analyzing MR tagging images with HARP software. Results: DE occurred in 21 (84%) patients with a high frequency of localization in the septum and the right ventricular attachment sites. Circumferential shortening was significantly decreased in the enhanced segments compared with nonenhanced segments (P < 0.0001). The myocardial wall was thicker in the enhanced segments than in the nonenhanced segments (P < 0.0001). However, circumferential shortening was significantly decreased in the enhanced segments of the same thickness (P < 0.0001). Circumferential shortening was more substantially impaired in the segments with focal nodular enhancement than those in the segments with ill-defined patchy enhancement (P = 0.0002). Conclusion: In HCM, DE is commonly found and circumferential shortening is significantly impaired in the regions with DE, regardless of the degree of myocardial hypertrophy. Focal nodular enhancement is particularly related with regional dysfunction in patients with HCM.

Original languageEnglish
Pages (from-to)1054-1060
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume27
Issue number5
DOIs
Publication statusPublished - 2008 May 1

Fingerprint

Hypertrophic Cardiomyopathy
Ventricular Septum
Gadolinium
Left Ventricular Function
Hypertrophy
Software

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Young, Jin Kim ; Byoung, Wook Choi ; Hur, Jin ; Lee, Hye Jeong ; Jae, Seung Seo ; Tae, Hoon Kim ; Kyu, Ok Choe ; Ha, Jong Won. / Delayed enhancement in hypertrophic cardiomyopathy : Comparison with myocardial tagging MRI. In: Journal of Magnetic Resonance Imaging. 2008 ; Vol. 27, No. 5. pp. 1054-1060.
@article{b2c29677fd114131b04be491456dbc47,
title = "Delayed enhancement in hypertrophic cardiomyopathy: Comparison with myocardial tagging MRI",
abstract = "Purpose: To evaluate the relationship between delayed enhancement (DE) and regional left ventricular function in hypertrophic cardiomyopathy (HCM) using gadolinium enhancement MRI and myocardial tagging MRI. Materials and Methods: Cine imaging, delayed enhancement Imaging, and tagging MRI were performed in 25 patients with HCM. The location, pattern, and extent of DE were evaluated. Circumferential shortening (Ecc) was obtained by analyzing MR tagging images with HARP software. Results: DE occurred in 21 (84{\%}) patients with a high frequency of localization in the septum and the right ventricular attachment sites. Circumferential shortening was significantly decreased in the enhanced segments compared with nonenhanced segments (P < 0.0001). The myocardial wall was thicker in the enhanced segments than in the nonenhanced segments (P < 0.0001). However, circumferential shortening was significantly decreased in the enhanced segments of the same thickness (P < 0.0001). Circumferential shortening was more substantially impaired in the segments with focal nodular enhancement than those in the segments with ill-defined patchy enhancement (P = 0.0002). Conclusion: In HCM, DE is commonly found and circumferential shortening is significantly impaired in the regions with DE, regardless of the degree of myocardial hypertrophy. Focal nodular enhancement is particularly related with regional dysfunction in patients with HCM.",
author = "Young, {Jin Kim} and Byoung, {Wook Choi} and Jin Hur and Lee, {Hye Jeong} and Jae, {Seung Seo} and Tae, {Hoon Kim} and Kyu, {Ok Choe} and Ha, {Jong Won}",
year = "2008",
month = "5",
day = "1",
doi = "10.1002/jmri.21366",
language = "English",
volume = "27",
pages = "1054--1060",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "5",

}

Delayed enhancement in hypertrophic cardiomyopathy : Comparison with myocardial tagging MRI. / Young, Jin Kim; Byoung, Wook Choi; Hur, Jin; Lee, Hye Jeong; Jae, Seung Seo; Tae, Hoon Kim; Kyu, Ok Choe; Ha, Jong Won.

In: Journal of Magnetic Resonance Imaging, Vol. 27, No. 5, 01.05.2008, p. 1054-1060.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Delayed enhancement in hypertrophic cardiomyopathy

T2 - Comparison with myocardial tagging MRI

AU - Young, Jin Kim

AU - Byoung, Wook Choi

AU - Hur, Jin

AU - Lee, Hye Jeong

AU - Jae, Seung Seo

AU - Tae, Hoon Kim

AU - Kyu, Ok Choe

AU - Ha, Jong Won

PY - 2008/5/1

Y1 - 2008/5/1

N2 - Purpose: To evaluate the relationship between delayed enhancement (DE) and regional left ventricular function in hypertrophic cardiomyopathy (HCM) using gadolinium enhancement MRI and myocardial tagging MRI. Materials and Methods: Cine imaging, delayed enhancement Imaging, and tagging MRI were performed in 25 patients with HCM. The location, pattern, and extent of DE were evaluated. Circumferential shortening (Ecc) was obtained by analyzing MR tagging images with HARP software. Results: DE occurred in 21 (84%) patients with a high frequency of localization in the septum and the right ventricular attachment sites. Circumferential shortening was significantly decreased in the enhanced segments compared with nonenhanced segments (P < 0.0001). The myocardial wall was thicker in the enhanced segments than in the nonenhanced segments (P < 0.0001). However, circumferential shortening was significantly decreased in the enhanced segments of the same thickness (P < 0.0001). Circumferential shortening was more substantially impaired in the segments with focal nodular enhancement than those in the segments with ill-defined patchy enhancement (P = 0.0002). Conclusion: In HCM, DE is commonly found and circumferential shortening is significantly impaired in the regions with DE, regardless of the degree of myocardial hypertrophy. Focal nodular enhancement is particularly related with regional dysfunction in patients with HCM.

AB - Purpose: To evaluate the relationship between delayed enhancement (DE) and regional left ventricular function in hypertrophic cardiomyopathy (HCM) using gadolinium enhancement MRI and myocardial tagging MRI. Materials and Methods: Cine imaging, delayed enhancement Imaging, and tagging MRI were performed in 25 patients with HCM. The location, pattern, and extent of DE were evaluated. Circumferential shortening (Ecc) was obtained by analyzing MR tagging images with HARP software. Results: DE occurred in 21 (84%) patients with a high frequency of localization in the septum and the right ventricular attachment sites. Circumferential shortening was significantly decreased in the enhanced segments compared with nonenhanced segments (P < 0.0001). The myocardial wall was thicker in the enhanced segments than in the nonenhanced segments (P < 0.0001). However, circumferential shortening was significantly decreased in the enhanced segments of the same thickness (P < 0.0001). Circumferential shortening was more substantially impaired in the segments with focal nodular enhancement than those in the segments with ill-defined patchy enhancement (P = 0.0002). Conclusion: In HCM, DE is commonly found and circumferential shortening is significantly impaired in the regions with DE, regardless of the degree of myocardial hypertrophy. Focal nodular enhancement is particularly related with regional dysfunction in patients with HCM.

UR - http://www.scopus.com/inward/record.url?scp=42949163894&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42949163894&partnerID=8YFLogxK

U2 - 10.1002/jmri.21366

DO - 10.1002/jmri.21366

M3 - Article

C2 - 18425835

AN - SCOPUS:42949163894

VL - 27

SP - 1054

EP - 1060

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 5

ER -